Synthesis of 1,3-Diaryl-7,7-diethyl-5-methyl-4-oxo-2-thioxo-1,2,3,4tetrahydro-7H-pyrano(2,3-d)pyrimidines.-The compounds (IIIa) and (Vb) display significant activity against Staphylococcus aureus, (IIId) and (Vd) against Escherichia coli and the derivatives (IIIc), (Va), (Vd) and (Ve) inhibit the growth of Aspergillus niger. -(AHLUWALIA, V. K.; BATLA, R.; KHURANA, A.; KUMAR, R.; Indian J.

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The question whether the species (III) or the isomeric species (VIII) is formed when the thiobarbituric acids (I) react with acetone/Et3N or mesityl oxide (II) is clarified by independent synthesis of (III) from (I) via the intermediates (V).

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Synthesis of 1,3-Diaryl-1,3-dihydro-5-(thiazol-4-yl)-2-thioxo-2H,5Hpyrimidine-4,6-diones.-The pyrimidine (Va) shows antibacterial activity against S. aureus, while (IIId) and (Vb) are found to be potent against E. coli. The compounds (IIIe) and (Vc) inhibit the growth of A. niger; (Vb) and (Vc) that of A. flavous.-(AHLUWALIA, V. K.; CHAUHAN, A.; KHURANA, A.; ARORA, K. K.; Indian J. Chem., Sect. B: Org. Chem. Incl.