Statins have an established role as cholesterol-lowering agents, and this study demonstrates that they also potentially have an anti-inflammatory effect in healthy male volunteers.
Congenital heart defects (CHD) are the most common type of birth defects and account for approximately one-third of all major congenital anomalies. 1 Worldwide, the prevalence has been increasing over time, and CHD now affects 1.35 million newborns every year. 1 With advances in cardiology and cardiac surgery, 90% of these patients survive into adulthood where they are then at risk of various late complications including arrhythmia, heart failure, pulmonary hypertension, and sudden cardiac death. 2,3 Although the incidence of heart failure in adult congenital heart disease is not well defined, the prevalence is thought to be increasing and now represents the
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