Introduction. Quality of life, objective assessment criterion of which is level of human’s needs and interests satisfaction, is primarily connected with health status. This is why so called “health-related quality of life” is closely associated with patient’s well-being and satisfaction of those aspects of life, that are impacted by disease or treatment process. During the study of oral health related quality of life (OHRQoL, 1996), most authors take the OHIP (Oral Health Impact Profile, G.D. Slade, A.J. Spencer, 1994) approach as a basis, such as OHIP-EDENT (Short Version). Due to the fact, other methods of quality of life assessment are not widely used in dental practice, and it is important to develop new approaches in quality of life study, combined with prosthetic treatment results, considering the appropriate indicators of oral health. The aim of this study is to conduct a personalized dental health indicators assessment reflecting patients’ quality of life after restoration of mandibular dental arch with overdentures. Materials and methods. Main group (MG) comprised 23(54,8%) female patients and 19 (45,2%) males ones (n=42) aged 56-89, whom mandibular overdentures with ball attachments were constructed. Comparison group (CG) consisted of 17(47,2%) women and 19(52.8 %) men (n=36) aged 57-76, who have been using first-timely constructed complete removable mandibular dentures for three years. After use of the Dental Profile Questionnaire, and after detailed anamnestic study, the number of patients’ of both groups responses about possible unfavourable symptoms in use of dental prostheses and the mean value of frequency of those symptoms (1- sometimes, 2- often, 3- mainly) were estimated. Statistical processing of data obtained was performed by standard methods of variation statistics using Statistica 6.0 Program. Results and discussion. The subjective component of our treatment results evaluation of in-depth analysis, after all reflected in extended description of the clinical cases in MG patients development of the current disease — significant loss of teeth with mandibular single remaining teeth / roots (K08.9 according to ICD-10) indicated that quality of life level of these individuals has a close connection with their oral health. According to the overall subjective evaluation of prosthetic treatment results after answering 14 patient’s oral health- related questions, the number of reports of adverse events was markedly different -22.7% in MG patients after 12 months of observation vs. 77.3% of CG patients, and statistically significant (p <0.05) - the decrease in the average score of their frequency. Thus, it can be argued, that in the MG patients satisfaction with the treatment results, that reflected the quality of life level, associated with oral health, was notably higher, than in the CG patiens. So, the dentures were identified applicable (pp.1-6) by 90.9% of MG patients vs. 54.6% of CG patients, accompanying signs (pp.7-12) were positively evaluated by 90.1% vs. 69.0%, and subjective well-being (pp.13-14) was acheived in 90.5% vs. 63.9% of patients in these groups. Conclusions. Results of the research have defined the improvement of all the 14 studied oral health indicators in patients of the main group after 1 year of the examination compared with the previous data after 1 and 6 months of mandibular overdentures use. Patients’ satisfaction with treatment results, reflecting the quality of life level, associated with oral health, confirms the higher efficiency of overdentures use compared to complete removable dentures in mandibular dental arch restoration.

Ëüâ³âñüêèé íàö³îíàëüíèé ìåäè÷íèé óí³âåðñèòåò ³ìåí³ Äàíèëà Ãàëèöüêîãî 2 Êàôåäðà îðòîïåäè÷íî¿ ñòîìàòîëî´³¿ (çàâ.-ïðîô. Êîðä³ÿê À.Þ.) 3 Êàôåäðà ïàòîëî´³÷íî¿ àíàòî쳿 òà ñóäîâî¿ ìåäèöèíè (çàâ.-Ïîñï³ø³ëü Þ.Î.) 4 Ñòîìàòîëî´³÷íèé ìåäè÷íèé öåíòð (äèðåêòîð-äîö. Øèá³íñüêèé Â.ß.) 5 ÊÇ ËÎÐ Ëüâ³âñüêèé îáëàñíèé êë³í³÷íèé ïñèõîíåâðîëî´³÷íèé äèñïàíñåð (ãîëîâíèé ë³êàð-ߺ÷íèê Â.Â.

The growing requirements for the quality of dental care necessitates expert evaluation of dental prostheses. Therefore, on the way to improve the structure and process of providing dental care, it is important to analyze the primary data of its results in quantitative and qualitative terms. The purpose of this work is to clarify the content and results of consulting care by analyzing clinically important indicators of the quality of fixed dentures that determine their applicability for further use. Among the 410 patients aged 35-81 examined for damage to abutment teeth and periodontal tissues, unsatisfactory condition of crowns and bridges, the 1st subgroup included 76 (18.5%) persons who sought counseling on their own initiative and the 2nd subgroup – 334 (81.5%) persons with referrals from other medical institutions. Quality indicators of 759 artificial crowns and 803 bridges were determined (K08.5 – unsatisfactory restoration of teeth) in the early (up to 24 months) and remote (more than 24 months of use) periods of observation using a modified index of clinical and technological quality. In patients of both groups in the early observation period 67 crowns and 101 bridges (all signs – 253), and in the remote period – 692 crowns and 702 bridges (3804 signs) of low quality were revealed. Quality index of these structures in the early and remote periods of observation was 0,71 versus 0,36 (p<0.05) and 0.64 versus 0.37 respectively (p<0.05). In 71 (93.4%) patients of the 1st group grounds for replacement of 292 out of 327 (89.3%), and in 238 (71.3%) patients of the 2nd group – 827 (67.0%) out of 1235 fixed partial dentures were found. Thus, expert assessment of the quality of dental care is an integral part of ensuring the predicted results of prosthetic treatment. The proposed method of assessing the clinical and technological quality of fixed dentures makes it possible to determine their suitability or unsuitability for further use.

A 8 0 7 -A 9 1 8 identified in the database. The randomized trial observed mean time to heal of 10.5 and 27.6 days for HCD and SSD, respectively (incremental effectiveness of -17.1 days). Evidence from smaller observational studies have reported intervals to HCD change of up to 14 days, while SSD requires two changes per day. Thus, the model estimated costs for the inpatient period assuming one dressing change for HCD and 28 for SSD. Cost per dressing change was estimated as 17.30BRL (BRL= Brazilian Reais) for HCD and 15.58BRL for SSD and overall treatment costs were 1,367.94BRL and 3,548.26BRL, respectively. Healthcare-related incremental costs were -1.72BRL indicating a cost-saving profile. Benefits in terms of reduction in length of stay were not accounted in this case based scenario. If average public hospital daily charges were included in the cost estimation, savings would reach -2,180.32BRL per patient or -479,617,192.42BRL for the cohort. ConClusions: HCD dressing has shown higher clinical efficacy when compared to SSD, with fewer overall costs, representing a robust cost reduction profile.Singapore objeCtives: Despite increasing use of economic evaluation to inform decisionmaking in Asia, decisions were made in the face of uncertainty due to poor quality evidence, if not absent. As wrong decision made comes with costly opportunity loss, value of information (VOI) analysis can provide a rational approach by estimating the monetary value of reducing uncertainty through future additional research. This study aims to investigate the use of VOI in a case of selection of strategies in the prevention of carbamazepine (CBZ)-induced Stevens-Johnson syndrome and toxic epidermal necrolysis among newly-diagnosed epilepsy patients in Malaysia. Methods: A hybrid model of decision tree and Markov model was developed to evaluate three strategies -(i) CBZ initiation without HLA-B*15:02 genetic screening (reflecting current practice); (ii) universal HLA-B*15:02 genetic screening prior CBZ initiation; and (iii) alternative treatment (valproic acid) without HLA-B*15:02 genetic screening. This analysis undertook the societal perspective over a lifetime time horizon. The population expected value of perfect information (PEVPI) and partial EVPI (EVPPI) were calculated for the three model parameter subsets: probabilities, direct medical costs, and utilities. A 10-year expected lifetime of the technology was assumed. Results: Based on a 10-year stream of 72,422 newlydiagnosed epilepsy population, the PEVPI was MYR739 million (USD185 million) at a willingness-to-pay threshold of MYR36,000 (USD9,000) per quality-adjusted life-year (QALY). The EVPPI results suggested that direct medical costs subset represented the largest amount of uncertainty, at MYR736 million (USD184 million). The EVPPIs of probabilities and utilities subsets were relatively modest at MYR18 million (USD5 million) and MYR11 million (USD3 million), respectively. ConClusions: This study demonstrated that VOI analysis is useful in quantifying and decreasing uncerta...

A563 age distribution. Results: A total of 4739 questionnaires were analysed yielding an overall prevalence of acne of 10.6% [9.7%-11.5%] in the Mexican population. The prevalence of acne decreased with age, ranging from 21.4% [19.1%-23.6%] in age group 15-24 to 9.9% [8.4%-11.3%] and 3.6% [2.7%-4.4%] in age groups 25-39 and 40-65, respectively. Severity of acne was reported as mild or moderate by over 90% of participants with acne and was consistent across all age groups. Results from a multivariate regression on the subgroup of participants aged 15-24 years, demonstrated that dietary habits such as consumption of dairy products and fried food were risk factors for developing acne whereas occasional alcohol consumption and duration since smoking cessation above 1 year appeared to be protective. ConClusions: Self-reported acne in Mexico is a frequent skin disease although less prevalent than reported in a European survey. Dietary habits were identified as risk factors for developing acne in the 15-24 age group.