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We present clinical case of portal vein thrombosis at the liver cirrhosis patient with signs of severe decompensation of liver function and portal hypertension. A feature of this case is that after consumption of alcohol condition of the patient was estimated erroneously as alcoholic hepatitis with high Maddrey index (105). However, later diagnosis of portal vein thrombosis was confirmed. The cancellation of antiinflammatory therapy and administration of anticoagulants allowed to stabilizate of critical situation. Thus, the clinical experience has shown that dopplersonography is necessary at the liver cirrhosis, especially in case of decompensation.

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