In the literature there is no complete data on the use of slaked lime as a disinfectant disinfectant. All veterinary publications indicate that a 10 - 20% solution of slaked lime has a disinfecting effect. However, the technology of carrying out, as well as modes of disinfection, are not specifically indicated in any literature. There is no data on which infectious diseases they affect, at what concentration, exposure and consumption of the disinfectant it can be applied, on smooth or rough surfaces, the frequency of whitewashing or wet disinfection, etc. Until now, the issue of the solubility of slaked lime in water and other chemical compounds has not been completely resolved. In addition, the lack of a disinfectant - 10 - 20% slaked lime, is a low disinfection efficiency, high corrosion activity in relation to metal products, a large flow rate of a solution of 1 -1.5 l / m2, which is carried out 2 - 3 times by whitewash.

Veterinary practice constantly needs highly effective, environmentally friendly, economically viable, non-specific means of protecting of animals from infectious diseases. It is known that various disinfectants are used for disinfection by irrigation, including: 5% hot solution of soda ash, 3% hot emulsion of disinfecting creolin, 1-2% formaldehyde solution, 2% sodium hydroxide solution, 5% chloramine solution, 1% glutaric solution aldehyde and others, calculation 0.5-1.0 l/m2 of the surface of the objects of veterinary surveillance. The disadvantage of these disinfectants is that many of them are toxic for humans and animals, have very irritating actirn on the respiratory tract, as well as the mucous membranes of the eyes. Also is known a disinfectant calcium hydroxide (slaked lime) of 10-20% concentration for the disinfection of objects of veterinary surveillance. This tool in comparison with the above mentioned is not particularly toxic and environmentally unsafe for the environment. The disadvantage of slaked lime is the low bactericidal activity against infectious diseases of the 1,2,3 category of resistance. It was found that 10% and 15% solutions do not disinfect Escherichia coli (pcs. 1257) and Staphylococcus aureus (pcs. 209 r), and 20% solution of hydrated lime disinfects Escherichia coli only after cross-application in 3 hours on smooth surfaces (stainless steel, galvanized iron, tile) and after 24 hours on rough surfaces (wood, concrete), at the rate of 1.0 l/m2. To increase the bactericidal and disinfection activity, 1.3 and 5% sodium chloride solution was added to a solution of 20% slaked lime. In this case, calcium chloride (CaCl2) and sodium hydroxide (NaOH) are formed, which can increase the disinfection activity by increasing the ionic strength of slaked lime solution. As experiments showed, the addition of 1% solution of sodium chloride in 20% solution of hydrated lime contributed to the disinfection of Escherichia coli and Staphylococcus aureus for 3 hours of exposure at rate of 0.5 l/m2, and rough -for 3 hours, at a rate of 1.0 l/m2. When 3% sodium chloride solution was added to 20% slaked lime solution, disinfection of smooth surfaces from Escherichia coli occurred in 1 hour, on rough surfaces in 3 hours at the rate of 0.5 and 1.0 l/m2, respectively. Staphylococcus aureus was disinfected on smooth surfaces in 3 hours at a rate of 0.5 l/m2, and on rough surfaces in 3 hours at a rate of 1.0 l/m2.

The creation of highly effective, environmentally safe and cheap disinfectants is a priority task of veterinary science, for the rehabilitation of veterinary surveillance facilities. The article presents the results of laboratory tests of a new product «Penox-2» for simultaneous disinfection and whitewashing of veterinary surveillance objects. Museum cultures of Escherichia coli (1257 pieces), Staphylococcus aureus (209P pieces), mycobacteria (1257 pieces) were used as test microorganisms. (pieces B-5) and Bас. сereus (pieces 96). To simulate the natural contamination of test surfaces, inactivated blood serum from loschad was used. The quality of disinfection was studied by examining flushes from experimental and control test surfaces for the presence of a given test culture. At the same time, it was found that solutions of the drug «Penox-2» disinfects Escherichia coli on smooth surfaces for 15 minutes, and Staphylococcus aureus for 30 minutes, at the rate of 0.25 – 0.3 l / m2. Disinfection of Escherichia coli on rough (concrete, wood) test surfaces took place in 30 min., Staphylococcus aureus in 1 hour, at the rate of 0.5 l / m2.For decontamination of test surfaces contaminated with mycobacteria, a single irrigation with a solution of «Penox -2» was required, for 3 hours of exposure, and for spores You. cereus, with double irrigation, at the rate of 0.5 l / m2, exposure 3 hours. The results of research have shown that the solution of the drug «Penox-2» is an effective disinfectant against gram-positive and gram-negative microorganisms.

One of the most important problems of the national economy is the protection of metal from corrosion, causing great damage to products and structures, shortening their useful life. Taking into account the importance of protecting metal structures of livestock objects from corrosion during disinfection work, the corrosion properties of the new Penox-1 disinfectant have been studied. Studies have shown that the tested drug «Penox-1» has a low corrosion activity in relation to metal products made of aluminum, galvanized iron and stainless steel, compared with the reference drug. Thus, the solution of the Penox-1 preparation reduced the initial weight of metal plates during 24 hours of exposure from aluminum by 0.196 g, which is 7.4%, and the standard preparation by 0.836 g or 32.1%, which is 4.3 times more . Similar data were obtained in a comparative aspect with galvanized iron and stainless steel plates. When examining metal plates after testing in a Penox-1 solution, the color and structure did not change visually and under a microscope. At that time, the plates immersed in a 2% sodium hydroxide solution changed strongly in color and structure, and a yellow-gray corrosive coating appeared.

The search of new disinfectants with a wide spectrum of antimicrobial activity of low toxicity and not hazardous in use, not requiring of creation of special storage conditions, convenient in use and not adversely affecting on processed items, affordable, is an urgent task of veterinary science. The article presents the results of laboratory tests of new bactericidal compositions, which include: 20% hydrated lime, 1.3 and 5% sodium chloride, as well as foaming agent PO-6K on test surfaces made of stainless steel, galvanized gland, tile, wood and concrete. As a test of microorganisms, museum cultures of E. coli (strain 1257) and Staphylococcus aureus (strain 209-P) were used. During the experiments, disinfection regimes were established (concentration, exposure, consumption of disinfectant) for disinfecting of smooth and rough test surfaces. At the same time, it was found that slaked lime solutions of 10 and 15% concentration did not have disinfecting activity even after triple whitening or irrigation of test surfaces contaminated with E. ooli (strain 1257), St. aureus (strain 209-P) at a rate of 0,5 l/m2 for smooth and 1 l/m2 - for rough surfaces. 20% solution of slaked lime, which destroys only Escherichia coli on smooth surfaces in 3 hours of exposure at the rate of 0,5 l/m2, and rough surfaces in 24 hours of exposure at the rate of 1,0 l/m2, has a disinfecting effect. At the same time, adding 1,3 and 5% sodium chloride to the slaked lime solution, the disinfecting activity of slaked lime also increases sharply; adding to 20% slaked lime 3 and 5% sodium chloride disinfects Escherichia coli and staphylococcus in 3 hours, based on smooth 0,5 l/m2, and for rough surfaces - 1 l/m2. Studies have also found that the addition of 3-5% sodium chloride, 5% foaming agent to 20% slaked lime solution reduces the consumption of the disinfectant in 2 times without reflecting the indicators of disinfection efficiency. When a foaming agent is added to the solution, the resistance (adhesion) of the foam on the vertical and ceiling surfaces increases on 14-18 minutes, and on the floor the foam is held in 1-1,5 hours, which helps to reduce the runoff of the solution.