Highlights Less invasive technique through small mucosal incisions. Overcomes the disadvantages of the traditional procedures. Minimal lingual histopathological changes. No serious complications were reported. Self-sucking was abolished and animal behavior changed.
ABSTRAcT. The uterine tissue of three healthy nonpregnant goats was evaluated experimentally as a graft for closure of a bladder defect. Goats were subjected to ovariectomy, and then one detubularized uterine horn was used as a graft to close a large defect in the ventral aspect of the bladder. Follow up included monthly radiographic and ultrasonographic examinations and evaluations of kidney function and electrolytes changes for six months. The goats were euthanized after six months, and both the bladder and the graft were examined macroscopically and histologically. The technique required less invasive procedures than those described with alternative techniques of cystoplasty, achieved a high survival rate without life-threatening complications post surgery, was associated with no significant changes in kidney function and electrolytes levels, showed proper healing of the transplanted graft by regeneration rather than repair without scaring or fibrosis and with complete covering of the graft by a healthy urothelium and was associated with no malignant transformation. Hysterocystoplasty is a noninvasive, non-life-threatening technique due to the close position of the bladder to the uterus, and proper healing of the graft reflects absence of pressure on its blood supply. It is an acceptable alternative technique for closure of a large bladder defect and avoids disadvantages of alternative techniques of cystoplasty. It might be accepted by owners of pets, and further studies in clinical cases of dogs are advised. Although cystoplasty is a historic topic that has been discussed well in scientific literature and argued at legendary proportion among urologists, the search for an ideal organ to replace a diseased bladder remains elusive for reconstructive urologists [32]. Many augmentation cystoplasty or neobladder techniques have been used routinely for treatment of reduced bladder compliance and capacity secondary to bladder infection and inflammation [27], neurogenic dysfunction or congenital bladder disorders [16], detrusor over activity [10], large bladder defects [8,9], bladder necrosis [30] and bladder tumors [7,12]. Although encouraging animal and human results have been reported with different techniques, each technique had its own limitations, complications and disadvantages [2,4,11,27].The ileum and colon have been used for decades for reconstruction of the bladder, in spite of the harmful contact of urine with the mucosa of the augmenting patch [23], which is predisposed to multiple short-and/or long-term complications like chronic bacteriuria or mucous secretion [1,23], stone formation [1,11,29], disturbance of calciumphosphate metabolism with potential bone growth retardation [24,28], altered hepatic and electrolyte metabolism [24], gastrointestinal motility disorders [23], augmenting patch perforation [1,6] and malignant transformation of the augmenting patch [1,14].Gastrocystoplasty has been described as an alternative technique; unfortunately, as the popularity of gastrocystoplasty increased, so did ...
A pre-clinical experimental study was used to evaluate a new intralingual suture pattern, for treating farm animal's tongue-wounds. Experimental section was performed on 36 fresh goat's tongue-samples, to compare the new suture pattern with the traditionally used two patterns (double rows simple interrupted pattern; and tension relieve vertical mattress with deep row simple interrupted pattern that is followed by superficial opposing vertical mattress). Comparison involved the required stitches number, duration of suturing, and pattern's tensile strength. The main clinical study was carried out on recent lingual wounds of variable depths which involved 30-50% of tongue width in one horse, one camel, one buffalo-calf, and three donkeys. In addition to three donkeys had old lacerations which failed to heal by first intension. Wounds sutured by the new pattern were covered by one row of cruciate mattress to oppose the mucosa. Results revealed that the new pattern required fewer stitches numbers, consume lesser time, had higher tensile strength, it could be easily applied, achieved proper apposition of both the muscular layer and mucosa, and it induced minimal scar formation and deformity. The technique is widely acceptable by the owners than the other traditional methods. The technique is advised to be used as an alternative suture pattern for the repair of lingual wounds in farm animals.
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