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HighlightsThe unilateral form of lipoma Arborescens affecting the knee is the most common, with a predilection for supra patellar recess.The clinical examination finds symptoms of chronicity, such as progressive soft swelling, pain, stiffness and episodes of joint blockage.MRI is the examination of choice showing multiple villous proliferation of the synovial and frond-like structures with a fatty signal.Treatment with intra-articular injections of radioactive compounds, such as Yttrium 90 or steroids, relieves symptoms during moderate periods.Early synovectomy offers the best functional outcome.

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