Behçet’s disease (BD) is a vasculitis with multisystemic manifestations. Articular involvement is frequent and benign whereas vascular complications are rare but serious and can form the onset of the disease. The assessment of the thickness of the common femoral vein wall is a new tool for the diagnosis of BD with good sensitivity and specificity. We report the case of a 52-year-old man diagnosed with BD revealed by an abdominal aortic pseudoaneurysm and a chronic monoarthritis. The first flare-up of BD can occur in men over 50 years of age. In a context of a multisystemic disease, lumbar pain should lead to the search of abdominal aortic aneurysm. The assessment of the thickness of the common femoral vein wall is accessible and should be used especially in challenging cases.
The foot and the ankle are the usual localisations of diabetic neuroarthropathy. The knee is rarely affected. Diabetic neuropathy and microangiopathy also cause skin fragility causing trophic disorders and ulcers. Diabetic bullosa is rare. We report the case of a 19-year-old female patient with type 1 diabetes complicated by knee neuroarthropathy and diabetic bullosa.
Nonclassical celiac disease is a diagnostic challenge for the practitioner. We report a case of a 28-year-old Moroccan woman who had been experiencing polyarthralgia and joint swelling for 8 weeks, despite treatment with nonsteroidal anti-inflammatory drugs and corticosteroids. On physical examination, there was effusion in the proximal interphalangeal joints, metacarpophalangeal joints, wrists, knees, and ankles. Laboratory tests revealed microcytic anemia, elevated levels of inflammation markers, low ferritin, and a low vitamin D level. An upper gastrointestinal endoscopy was performed to investigate the cause of anemia, revealing the loss of duodenal folds. Subsequently, a duodenal biopsy was performed, and serological testing for celiac disease was requested. Anti-transglutaminase-2 antibodies were elevated at 200 U/ml (normal < 15U/ml). The duodenal biopsy showed flattened duodenal mucosal epithelium. The patient was diagnosed with celiac disease. A gluten-free diet was started. Her joint symptoms resolved in 3 weeks. All blood tests returned to normal levels after 48 weeks. This case illustrates that celiac disease should be considered in cases of arthritis with an initial negative etiological workup.
La dermatomyosite (DM) et la polymyosite (PM) sont des affections rares mais graves. Le but de ce travail est d'étudier, à travers la revue d'une série hospitalière, leur profil épidémiologique, clinique et évolutif. Il s´agit d´une étude rétrospective, conduite sur une période de 15 ans, entre janvier 2004 et décembre 2019. Ont été retenus les cas où le diagnostic était certain ou probable selon les critères de Bohan et Peter. Un total de 14 patients ont été inclus (8 DM et 6 PM), l´âge moyen était de de 48,7 ans. La sex-ratio était de 13F/1H. Les signes généraux existaient dans 71%. Le déficit moteur touchait les muscles des ceintures dans 71% des cas; 85,7% avaient des arthralgies et 14% des arthrites. L´érythème et l´œdème périorbitaire étaient les signes cutanés prédominants. Au bilan, la vitesse de sédimentation était accélérée chez tous les malades et les enzymes musculaires augmentées dans 80%. Les anticorps anti-nucléaires étaient positifs dans 63%. La biopsie musculaire a retrouvé une myosite inflammatoire dans 75%. L'atteinte cardiaque existait dans 14% des cas et pulmonaire dans 21%. Un cancer était associé dans 21,4% des cas. Tous les patients ont reçu une corticothérapie. L´évolution s´est faite vers l´amélioration dans 88%, avec une rechute chez 4 patientes. Dans notre contexte, la DM est plus fréquente que la PM, avec nette prédominance féminine. L'atteinte pulmonaire reste une complication lourde. L´association aux cancers semble fréquente d´où la nécessité d´un bilan systématique de néoplasie au moment du diagnostic et lors du suivi.
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