The rebirth and use of medicinal plants in aquaculture has become necessary as the use of synthetic drugs and chemicals is been discouraged due to their aftermath effects on cultured organisms and aquatic environment. A 56-day study was conducted to assess the effects of Roselle and ginger as dietary additives, on growth and hematology of Clarias gariepinus juvenile. Total of 150 C. gariepinus juveniles (35.41±1.45 g) were assigned to five iso-nitrogenous diets as treatments having ginger and roselle added as additives at varying inclusion levels of 0.0, 2.0, 4.0, 2.0 and 4.0 g/100 g. Best growth performance was observed in 4.0 g ginger treated fish followed by 4.0 g roselle fed fish group, while 2.0 g roselle fed fish had the lowest growth performance. Significant changes (p˂0.05) were observed in the haematology of C. gariepinus fed varying inclusion levels of ginger and roselle. Highest values for red blood cells (4.07±0.08), haemoglobin (11.61±0.57) and pack cell volume (34.33±0.88) were seen in 4.0 g ginger treatment group followed by the control (3.63±0.22, 9.93±0.92 and 30.33±2.73), respectively. No significant changes were observed in red blood cells indices (mean corpular volume, mean corpular hemoglobin and mean corpular hemaglobin concentration). The current study revealed that fish fed 4.0 g ginger diet had better growth and haematological profile.