Objectives To evaluate the characteristics and association with perinatal outcome of the aortic isthmus (AoI) circulation as assessed by Doppler imaging in preterm growth-restricted fetuses with placental insufficiency. Methods

Objective To evaluate the accuracy of four-dimensional (4D) spatiotemporal image correlation (STIC) echocardiography for the diagnosis of fetal congenital heart disease (CHD) in a selected high-risk population. Methods 91.6, 94.9, 88.1, 89.7 and 94.0%, respectively

Objectivesand location (OR 0.385 (95% CI,

K E Y W O R D S:congenital heart defects; early fetal echocardiography; early prenatal diagnosis; four-dimensional echocardiography; STIC ABSTRACT Objectives