Introduction: Uncoordinated data collection by different research groups prompted the initiation of Malaysian oral cancer Research Initiative (MOCRI) group. Objectives: To coordinate and standardize data and tissue collection and storage, develop a minimum dataset on risk factors, intervention techniques and quality of life of oral cancer patients. Materials and Methods: A computer software programme is currently being developed to accommodate multi-centre data collection and research activities in eight hospitals. The complete dataset includes parameters on sociodemographic, clinical, pathological, quality of life measures, details of treatment methods, vital status and dietary intake. Tissues are being collected, stored and catalogued as fresh and formalin-fixed tissues for future use in satellite researches. The networking in tissue and data collection includes the establishment of oral cancer cell-lines. These tissues are being planned for studies on genetic profile, genetic polymorphism, diagnostic and prognostic markers. Results: Tissues and data on 115 oral cancers, 9 leukoplakia and 13 lichen planus has been collected since 2003. Preliminary data from 2004 were analysed for 58 cancer patients. Majority of them are more than 60 years old (65.5%) with a mean age of 63.3. Twenty-four (41.4%) were males, 34 (58.6%) females with the majority of them being Indians (56.9%) followed by Chinese and Malays (15.5% each), Indigenous people of Sabah and Sarawak (12.1%). Eighteen (31%) respondents were smokers, 17 (29.3%) alcohol drinkers and 31 (53.4%) betel quid chewers. Five patients have had histories of family cancers where 3 included immediate family members with head and neck cancers. For the quality of life measure, only 30.2% felt that their daily activities were disrupted despite having advanced cancers. Satellite researches are in progress on genetic polymorphism and tumour markers. One oral cancer cell-line has been established. Conclusion: The establishment of oral cancer database and tissue bank in encouraging and supports ongoing satellite researches.
Introduction: Western researchers showed that oral squamous cell carcinoma (OSCC) patients exhibit lower survival rate and poorer prognosis compared to other type of cancer where several clinicopathological parameters have been implicated in the survival of patients. This study aims to assess the association between sociodemographic and clinicopathological parameters with survival of OSCC patients. Method: Data were collected from 253 histologically diagnosed OSCC patients attending selected clinics nationwide. Survival was analyzed for relation with habits, site, disease stage and nodal involvement.
Cardiovascular disease is one of the main health problems and causes of death in the world. M-Health (mobile health) has the potential to improve the prevention of disease recurrence by providing continuous intervention after treatment at a hospital. The purpose of this paper were to review health literature that examines the application of m-health as a preventive measure in cardiovascular disease patients, identify features contained in m-health applications and analyze the factors for implementing mobile health. The preparation of this literature review used various databases including EBSCO, Google Scholar, Science Direct, PubMed, and Sage Journal which was conducted from December 2018 to January 2019. In total, this paper used 6 journals reviewed with predetermined keywords: four journals with quantitative methods, one journal with qualitative methods, and one journal with mixed-methods feasibility. Then screening was done based on the specified inclusion and exclusion criteria. M-health can change healthy behavior post-treatment at a hospital and prevent recurrence in patients with cardiovascular disease, With remote health services health workers can easily monitor patients' health status. The factors that influence the application of m-health are the level of patient knowledge of technology, the level of awareness of prevention of cardiovascular disease, lack of motivation for smartphone use, and poor internet access in a remote area.
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