IRDUS can be useful, besides being highly useful in the diagnosis of graft primary dysfunction in the transplanted patient also yields information that can help to predict long-term graft survival.

A lgunas sustancias adictivas en las Américas se han producido y consumido desde tiempos inmemoriales. La hoja del tabaco y la de coca son clásicos ejemplos de ello. Sin embargo, hasta épocas recientes su consumo nunca tuvo repercusiones de salud pública especialmente serias. Hoy en día, el consumo de tabaco, alcohol y otras drogas

pathological stage, lymph node (LN) status, histological grade, vascular-lymphatic invasion, and SXR expression.• In multivariate analysis, independent predictors of OS were LN status (odds ratio [OR], 2.96; P = 0.034), vascular-lymphatic invasion (OR, 2.50; P = 0.029), and SXR expression (OR, 1.05, P = 0.03).• Among the 51 patients with negative LNs (pN0), univariate predictors of OS were SXR expression, MDR1 expression, and pathological stage. In multivariate analysis, SXR expression (OR, 1.06; P = 0.01) and MDR1 expression (OR, 3.27; P = 0.03) were independently associated with survival.• Within the pN0 group, patients with SXR expression had shorter progression-free survival than did those without expression ( P = 0.004). This association persisted in the N0 subgroup with stage pT3-pT4 disease ( P = 0.028). However, in the pN1 group SXR expression did not have any influence.

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