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ABSTRACT:Child birth is one of the most important events in the life of a woman. Though it is a physiological event it is painful. The pain experienced is beyond description and is basically due to process of cervical dilatation. The duration of the first stage is longest of the 3 stages of labour and it is due to painful progressive cervical dilatation. It is ideal for any obstetrician to achieve reduction of pain and suffering during labour by accelerating the rate of cervical dilatation. INTRODUCTION:The cervix is a cylindrical fibro-muscular component of the lower end of the uterus measuring 3cm in length and 2cm in thickness. 1 The cervical canal is 3cm in length extending from the internal os to the external os. The surrounding tissue components of cervical canal are fibrous, ground substance and cellular elements. The distribution of muscular component is 29% in upper 1/3rd, 18% in the middle 1/3rd, 6% in lower 1/3rd i.e., maximum at the level of internal os offering maximum contractile response to the advancing foetal head following uterine contractions. 2 The fibrous component predominantly contains fibrils and collagen fibres arranged in the form of bundles and the elastin fibres which are in the form of sheets interspersed with in the collagen. The elastin fibres are capable of stretching and returning to its original size. The ground substance contains glycosaminoglycans like dermatan sulphate and hyaluronic acid, the proteoglycans like decorin and biglycan. The decorin-collagen interaction is responsible for orderly arrangement of the bundles of collagen. 3,4

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The present study was undertaken to evaluate the changes of liver function tests and platelet count in different grades of PIH women. The study group included 90 PIH women divided into 3 groups based on the severity of PIH into 30 mild PIH, 30 preeclampsia and 30 eclampsia. The LFT parameters and platelet count were estimated. CONCLUSIONSLFT parameters like AST, ALT, ALP and Platelet estimation can be taken as an early interpretation for assessment of severity of PIH, so that early measures are taken to prevent the maternal and fetal complications. HOW TO CITE THIS

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