Early treatment of skeletal class III becomes necessary in growing patients to prevent the future deterioration of the existing malocclusion and avoiding the complex orthognathic surgical procedures to correct the same. This case series explains two different treatment modalities for growing patients with skeletal class III malocclusion with anterior crossbite, who have differing degree of growth potential, growth pattern, facial profile, lip competency and strain, amount of skeletal discrepancy, and intra-arch relationships. The treatment goals have been achieved efficiently in each situation, due to prompt diagnosis and utilization of proper treatment mechanics.

Periodontally accelerated osteogenic orthodontics, a newly evolved technique, involves a combination of corticotomy followed by placement of bone graft and orthodontic force application for the closure of extraction space. This interdisciplinary approach has solved the issue of increased treatment duration by accelerating extraction space closure. The index case describes corticotomy procedure done using piezocision technique along with platelet-rich fibrin placement that has enhanced tooth movement, improved wound healing, and reduced adverse effects including root resorption and damage to periodontium. It was concluded that the orthodontic tooth movement was increased postsurgery, thereby lessening treatment duration and patient discomfort.