Over a long time, exploration of the structural stability of single and poly-crystalline materials has been an attractive topic in materials science because it is crucially important to explore the stability of materials whereby it is possible to generate novel structures and identify materials with multifunctional properties. In the present work, we report the crystallographic structural stability of the poly-crystalline lead nitrate samples at shocked conditions with which a systematic comparison is made for the previously reported single-crystalline lead nitrate crystal at shocked conditions. X-ray diffractometry (XRD) and Raman spectroscopic measurements have been performed to assess the crystallographic structural stability of poly-crystalline Pb(NO3)2 samples at shocked conditions and the observed XRD and Raman results disclose that the title poly-crystalline samples retain the original crystallographic structure even at 100 shocked conditions interacting with the shock waves of 2.2 Mach number. But the single crystals of Pb(NO3)2 undergoes crystalline to amorphous phase transition at shocked conditions. Based on the observed results, poly-crystalline samples have higher-structural stability than that of the single crystals. The outcome of this work provides the glimpses of possible further contributions to crystal engineering for the design of new materials with specific physical and chemical properties as well as understanding the degree of shock resistance of single and polycrystalline materials.