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The present study has been undertaken to evaluate In-vivo Anti–hyperglycemic and anti–oxidant activities of ethanolic Lantana camara leaves extract (LCE). The extract was prepared by cold percolation process. Phytochemical screening indicates that the presence of flavanoids, phenols, carbohydrates etc. The Anti-hyperglycemic activity of the extract was studied by In-vivo using Streptozotocin induced diabetes rat models. Glibenclamide was used as a standard drug to compare the blood glucose level. The groups treated with Lantana camara leaves extract at dose 200 and 400 mg/kg prevented the diabetes condition in a dose related manner. LCE and Glibenclamide treated rats showed decreased LPO that is associated with increased activity of SOD and catalase. The increase in the level of lipid peroxides in plasma generally is thought to be the consequence of increased production of and liberation in to the circulation of tissue lipid peroxides due to pathological changes. This action shows the Anti-peroxidative effect of LCE. The results obtained thus suggest that 50% ethanolic Lantana camara leaves extract possesses potent Anti-hyperglycemic and Anti-oxidant activity.

Studies on callus growth and shoots/cotyledon, using seven different genotypes of pigeonpea and their hybrid progenies, revealed continuous variation for these traits. Hence, the type of gene action influencing in vitro cell proliferation and differentiation has been investigated in a diallel analysis of seven pigeonpea genotypes. Highly significant average heterosis was recorded for callus growth and seed yield/plant. In general, the F1 hybrids which showed heterosis for callus growth also exceeded their better parent for yield/ plant. Combining ability analysis revealed both additive and non-additive gene effects for callus growth, while number of shoots/cotyledon was mostly governed by non-additive gene effects. The genotype, 'ICP 7035', was the best general combiner for callus growth and shoot forming capacity of cotyledons. Two cross combinations, '7186'×'6974' and '7035'×'T-21', showed maximum SCA effects for callus growth and shoots/cotyledon. Callus dry weight was positively correlated with seed yield/plant and seedling weight. The strong positive association of callus growth with seed yield indicates the possibility of using this system for mass screening and selection of superior hybrids.

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