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Background. Tuberculosis is an infectious socially significant disease. Apart from individual traits of the disease pathology, drug sensitivity and the availability of effective medicine and prevention, an important factor of its control is the patient’s social status. Social patient profiling in various locations across the country is vital for developing and deploying a high-quality and feasible tuberculosis care programme.Objectives. Social profiling of tuberculosis in St. Petersburg as an example of large urban area. Methods. We developed a questionnaire to assess 40 social parameters of a patient with tuberculosis. The study sample was representative and surveyed 666 (63.4%) and 704 (65.7%) patients with primary diagnosis in 2017 and 2018, respectively.Results. The survey showed almost no impact of external migration on tuberculosis epidemiology in St. Petersburg. Internal migrants counted 76 (11.4%) in 2017 and 96 (13.4%) in 2018, thus suggesting the majority of primary tuberculosis patients being permanent residents of St. Petersburg. The contribution of individuals with no fixed abode to the incidence rate was also insignificant, 2.4% and 1.9%. Most patients were unemployed people of working age, 236 (35.4%) in 2017, 261 (37.1%) in 2018. Incidence among students as a younger population was lowest, 2.1% and 2.8%. Smokers accounted for half of total patients, 370 (55.6%) and 368 (52.3%). One in five patients carried HIV infection, with half of them not receiving antiretroviral therapy. Patients with unfinished secondary education and residing in collective dwellings were significantly more frequent, whilst the proportion of persons with high income decreased. Over half of the patients had no family at primary diagnosis, and over a third had never been married.Conclusion. The social profile of primary tuberculosis in an urban area is as follows: single man, near 40 years old, permanent resident, unemployed, working-age, smoker, resides in private abode, has secondary or secondary vocational education, low to average income.

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