A new simple and efficient one-step method for the preparation of arylacetonitriles by reaction of b-(dimethylamino)styrenes with hydroxylamine hydrochloride in formic acid solution is described.
The action of various anionic O , N , and S nucleophiles on 3 cyano 4,6 dinitro benzo[d]isoxazole mostly resulted in regiospecific nucleophilic substitution for the nitro group in position 4. With an excess of an nucleophilic reagent, the nitro group in position 6 was also replaced.
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