Polyarteritis nodosa refers to the group of systemic vasculitides affecting small and medium arteries. It is characterized by inflammation of the vascular wall with the development of aneurysmus and thrombosis. The article presents a rare clinical case of polyarteritis nodosa, which has not been diagnosed for a long time and gives the description of the diagnostic search, performance of differential diagnosis as a result of which the diagnosis of systemic vasculitis has been defined.

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The article presents a clinical case of such difficult for detection disease assystemic lupus erythematosus (SLE), which is characterized by atypical debut options, rapid development of complications, inadequate response to therapy. It is emphasized that the first clinical manifestations of the disease are the most important for its timely diagnosis, beginning of treatment and prevention of complications. The study concludes that mistakes in the diagnosis, late beginning of treatment may be related to the absence of SLE awareness among physicians.

This article presents a clinical case of dissecting thoracic aortic aneurysm. The first clinical manifestations were typical symptoms of the disease. Timely diagnosis and treatment are particularly important to prevent a fatal outcome. Late diagnosis may be related also to the lack of doctors’ caution with regard to dissecting aortic aneurysm.

The article describes a clinical case of bronchial cancer without radiologic changes. This is often associated with late diagnosis of the disease and a high mortality rate of this pathology.