With the aim of improving productive potential of black pied cattle, preventing and treating clinical mastitis we used biopreparations developed by scientists of the Federal State Budgetary Establishment of Higher Education ‘Chuvash State Agrarian University’: Prevention-N-E and Prevention-N-B-S, as well as Mastinol, homeopathic medicinal product for treatment of mastitis. It follows from the results of our studies that the biological preparations used in the experiments did not influence the physiological condition of animals but activated cell factors of non-specific organism protection. The most obvious effect was demonstrated by Prevention-N-B-S, rather than Prevention-N-E, however this difference was insignificant (P>0.05). Prevention of mastitis in cows with Prevention-N-B-S biopreparation turned out to be more effective than with Prevention-N-E and Mastinol. Recovery of one cow of the 1st experimental group treated by Prevention-N-E took place in 4±0.08 days, which is 7±52 less than in the 3rd experimental group, where Mastinol was used. Atrophy of an udder lobe was observed in one cow in the 3rd experimental group. As a result, the issue of pathogenetic therapy of mastitis in cows is still relevant and we plan to solve it with the use of immunostimulants.

The article describes a method of preventing postpartum obstetric-gynecological diseases and improving cow reproductive function due to the increase of body nonspecific resistance with the application of electropuncture and biopreparation Prevention-N-C (Chuvash State Agrarian University, Russia) and Salus-PE (Chuvash State Agrarian University, Russia). The cows of the 1st group were injected three times 45-40, 25-20 and 15-10 days before calving intramuscularly at a dose of 10 ml/head with the biopreparation Prevention-N-C, and the cows of the 2nd group were injected according to the same scheme and the same term with Salus-PE, and the cows of the 3nd group electropuncture was performed on the Vocal-B device (BIORS, Russia) immediately after childbirth, three times, after 48 h. The use of biopreparations during critical periods of cow steeliness reduced the risks of subinvolution of the uterus, endometritis and mastitis in the postpartum period and increased the reproductive qualities of cows. It has been shown that after the use of Salus-PE, 100% of cows are fertilized, 60% of which are fertilized in the first sexual hunt, and 40% - in the second. The insemination index was 1.4.