We provide a self-contained quantum description of the interference produced by macromolecules diffracted by a grating, with particular reference to fullerene interferometry experiments. We analyze the processes inducing loss of coherence consisting in beam preparation (collimation setup and thermal spread of the wavelengths of the macromolecules) and in environmental disturbances. The results show a good agreement with experimental data published by Zeilinger's group and highlight the analogy with optics. Our analysis gives some hints for planning future experiments.Comment: 20 pages LaTeX, 8 figure

In diffraction experiments with particle beams, several effects lead to a fringe visibility reduction of the interference pattern. We theoretically describe the intensity one can measure in a double-slit setup and compare the results with the experimental data obtained with cold neutrons. Our conclusion is that for cold neutrons the fringe visibility reduction is due not to decoherence, but to initial incoherence.Comment: 4 pages LaTeX, 2 figure

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