A system for cell-culture real-time monitoring using an Oscillation-Based (OB) approach is proposed. The system transforms a Cell-Culture Under Test (CCUT) into a suitable "biological" oscillator, without needing complex circuitry for excitation and measurement. The obtained oscillation parameters are directly related to biological test, owed to an empirically extracted cell-electrode electrical model. A discrete prototype is proposed and experimental results with living cell culture are presented, achieving the expected performances.

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