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It has been shown that perfectionism is a precursor to passive procrastination, which is a form of self-regulation failure, but little is known about the role of perfectionism in active procrastination. Thus, we sought to determine the relationship of high standards and discrepancy with active procrastination, which is a functional form of procrastination linked to better academic performance and psychological well-being. A convenience sample of 175 undergraduate students completed the Almost Perfect Scale-Revised and the Active Procrastination Scale. The results show there was a negative correlation between discrepancy and active procrastination. Students who perceived a larger discrepancy between their own performance goals and their actual performance were less likely to procrastinate actively. This suggests that the influence of perfectionism on procrastination may extend to active procrastination. Therefore, the implementation of interventions aimed at reducing individuals' perfectionistic tendencies is of great importance.

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Posters (Monday) S247in layers 5-6. In contrast, CB+ GAD67+ bouton density was on average 36% lower in layers 5-6. To determine if these findings have a developmental origin, we are currently performing a study of CB+ bouton synaptic pruning in monkey PFC. The data from this study will also be presented. Conclusion:The increase in CB+ GAD65+ boutons in the superficial layers suggest that there is greater inhibitory regulation of pyramidal cell firing in these layers in schizophrenia. In contrast, there appears to be a deficit in inhibition from at least some CB+ neurons in the deeper cortical layers that could alter the synaptic input and output of pyramidal neurons in schizophrenia.M99 Background: Recent studies have identified abnormalities of retinal structure and function in schizophrenia. This study used flash electroretinography (fERG) to examine retinal cell function in schizophrenia and determine under which conditions schizophrenia patients were most impaired. Methods: fERG data were collected on 20 schizophrenia patients and 25 healthy controls. Data were averaged over both eyes and collected under both light-and dark-adapted conditions. The primary variables of interest were a-wave activity (reflecting photoreceptor response) and b-wave activity (reflecting primarily bipolar cell activity).Results: On light-adapted (photopic) tests, schizophrenia patients demonstrated significantly weaker photoreceptor response when a flash was presented against an unlit background, and during a steady-state flicker test, but not when light was flashed against a lit background. On darkadapted tests, both groups demonstrated a linear increase in photoreceptor response with increases in stimulus intensity, but the rate of response gain per unit of intensity increase was significantly weaker for patients than controls. In both light-and dark-adapted conditions, patients demonstrated weaker signaling of bipolar cells, except when stimulus intensity was weak. Multivariate analyses indicated that the schizophrenia and control groups could be strongly discriminated by a combination of 3 fERG variables related to photoreceptor and bipolar cell function. Conclusion: These data suggest that both reduced signaling of photoreceptor and bipolar cells, as well as attenuated amplification of response under conditions of increasing stimulus intensity, are associated with schizophrenia. Moreover, both rod and cone responses appear to be affected. M100. AMPA RECEPTOR SUBUNIT EXPRESSION AND RECEPTOR BINDING IN PATIENTS WITH SCHIZOPHRENIA: A SYSTEMATIC REVIEW OF POSTMORTEM STUDIESHideaki Tani* ,1 Takefumi Suzuki, Shinichiro Nakajima, Masaru Mimura, and Hiroyuki Uchida Keio University School of Medicine Background: While altered trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors has been reported in schizophrenia, the findings widely differ among studies. In this systematic review, we examined published data from postmortem studies that investigated the AMPA receptor expression in schizophrenia. Methods: ...