: An emergency can be encountered anytime and anywhere. Minimal knowledge about medical emergency and their etiology, primary protocol for management must be known to avoid potential consequences. Hence, the present study was undertaken to compare the knowledge, and ability to handle the medical emergencies among the dental students. A cross-sectional survey was conducted among 100 randomly selected dental students (post-graduate students and interns) comprising of two groups of students those who had underwent training and those who did not. The data obtained was analyzed using the SPSS for windows version 22.0 released 2013. Independent chi square test was used for comparison of responses and independent student t-test was used for the comparison of mean scores. The significance level was set at p<0.001. : The average mean knowledge and ability score was 68% & 61.4% respectively among the participants. On further comparison of mean knowledge & ability scores between the participants with & without basic life support training, participants with BLS training showed better knowledge than those without training and the difference was statistically significant between the two groups (p<0.001%). The study found deficiencies in the knowledge and ability of untrained graduates to deal with medical emergencies as compared to trained.