Chondrosarcoma is the second most frequent malignant bone tumour after osteosarcoma. It most often occurs in the pelvis. Treatment of pelvic chondrosarcoma is a difficult problem for the musculoskeletal oncologist. We report 3 patient with chondrosarcoma in pelvic region that undergoing internal hemipelvectomy. First patient, male 28 y.o. with chondrosarcoma in left iliac wing 11.2cm x 10.8cm x 9.2cm. Second, woman, 47 y.o with chondrosarcoma in right superior and inferior pubic rami 13.7cm x 11.5cm x 14.2cm with soft tissue mass around extended to medial part of proximal thigh. Already done A wide excision of the tumor was performed and we use non-vascularized fibular graft (NVFG) to fill the defect. Last patient, pregnant woman 22 y.o. (16weeks gestational age) with chondrosarcoma in right pubic rami 9.8cm x 11.4cm x 13cm. We already done internal hemipelvectomy without terminating the fetus. The second and third patient confirmed with the histopathology result with chondrosarcoma grade II, and the first patient with chondrosarcoma grade I. After 3month post operatively, all of the patients have no pain, no urinary tract complain. The first patient can ambulatory full weight bearing with no crutches or walker. Second patient ambulatory partial weight bearing with crutches. The last patient ambulatory with wheel chair during the pregnancy. Since chondrosarcomas are unresponsive to chemotherapy or radiotherapy, surgical resection was the only therapeutic solution for these patients. It also reinforce the need of a correct diagnose and collaboration between specialities in the treatment of oncological patients.

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A 30-year-old man presented with a swelling below the left side of the jaw extending to the floor of the mouth since two months. He also gave a history of difficulty in speaking as the swelling interfered with the movement of the tongue. He reported loss of weight over one month. He had no other significant past history and did not smoke or drink alcohol. On examination, there was a diffuse swelling in the left jaw extending to the floor of the mouth in the left side which was about 3 cm from the tip of the tongue. It was firm in consistency with an irregular edge and smooth surface. The skin over the swelling was adherent to the underlying mass. The clinical diagnosis of malignant tumour of the left submandibular gland was made. No lymph nodes were palpable at the time of presentation and the clinical stage was T 3 N 0 M 0 .An ultrasound of the neck was done which suggested a diagnosis of left submandibular neoplasm. CT scan of the head and neck revealed submandibular gland tumour b]. Fine Needle Aspiration Cytology (FNAC) of the left submandibular salivary gland was done and it was suggestive of poorly differentiated malignant neoplasm of the left submandibular salivary gland. The tumour cells were in irregular clusters showing moderate cellular and nuclear pleomorphism with focal nuclear moulding and moderate amount of cytoplasm. Chest X-ray, endoscopy and whole body scan were done to exclude pulmonary lesions and distant metastasis. Patient underwent surgical resection and specimen was sent for histopathological evaluation.Grossly, an irregular grey brown tissue mass measuring 7.5 x 5.5 x 3.5 cm was received. The outer surface had attached normal salivary gland with skin on one side of the mass along with muscle and two lymph nodes. The cut surface showed an irregular homogenous grey white lesion with areas of necrosis [Table/ Fig-2].Microscopically, the submandibular salivary gland showed the presence of infiltrating tumour. Tumour cells were small round with round to oval nuclei and scanty cytoplasm in the fibrovascular stroma. The cell border was ill defined with nuclear moulding. There was also focal area of perineural invasion. Tumour cells were seen penetrating the submandibular salivary gland and extending into the dermis, not invading epidermis. There was no evidence of tumour infiltrating the adjoining skeletal muscle and isolated lymph nodes [Table /Fig-3a,b]. The histopathological diagnosis of SCC of left submandibular gland was given. The tumour was in clinical stage of TNM stage III (T 3 N 0 M 0 ). AbSTRACTSmall Cell Carcinoma (SCC) of the salivary gland is a rare and aggressive tumour accounting for about less than 1% of the salivary gland tumours. Submandibular gland involvement is extremely rare. These tumours frequently present with metastasis to lymph node and distant organs. We report a case of a 30-year-old male patient who presented with a swelling on the left side of the face below the jaw and the floor of the mouth. The tumour was excised followed by histopathological evaluation and d...