Microwave-promoted iminyl radical cyclizations can be terminated by trapping with TEMPO, affording functionalized adducts. The use of alkynes as radical acceptors delivers a range of 2-acylpyrroles in good yields. Toxic and hazardous reagents, which are frequently employed in radical reactions, are not required. The O-phenyl oxime ether substrates are constructed in a single step from readily available ketones.

The mild protocol does not require toxic or hazardous reagents and tolerates a variety of functional groups including acid and base labile ones. -(CAI, Y.; JALAN, A.; KUBOSUMI, A. R.; CASTLE*, S. L.; Org. Lett. 17 (2015) 3, 488-491, http://dx.doi.org/10.1021/ol5035047 ; Dep. Chem. Biochem., Brigham Young Univ., Provo, UT 84602, USA; Eng.) -F. Schill 25-148