The reaction between benzensulfonyl chloride and aniline was studied in various compositions of methanol with ethyl acetate, propan-2-ol and water at 25 C. Second-order rate coefficients of this reaction were determined; those in pure solvents were in the order of water4methanol4propan-2-ol4ethyl acetate. Rates decreased sharply with the mole fraction of ethyl acetate in methanolethyl acetate mixtures and showed an increasing trend with water content in methanol -water mixtures. Linear free energy relationship regressions showed that the polarity, hydrogen-bond donor ability and hydrophobicity of the media were the main factors affecting the reaction rate coefficient.

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