Automatic lesion segmentation is an important part of computer-based image analysis of pigmented skin lesions. Currently, there is a great interest in the development of Computer-Aided Diagnosis (CAD) systems for dermoscopic images. The segmentation step is one of the most important ones, since its accuracy determines the eventual success or failure of a CAD system. This study introduced new method of dermoscopic images segmentation. The preprocess was the filtering operation to dermoscopy image to remove most of difficulties facing the efficient segmentations, like a variety of lesion shapes, sizes, color, changes due to different skin types and textures and presence of hairs. Segmentation based mainly on histogram thresholding. The enhancements of image achieved by using mathematical morphology in order to obtain better segmentation with smooth border and without any noise in the lesion region. The proposed method evaluated by using Hammoude Distance (HM) and the True Detection Rate (TDR). Also the proposed method is compared with other skin lesions segmentation methods such as Otsu, adaptive thresholding and fuzzy Cmeans. The accuracy of proposed method was 96.32%, which is highly promised result and dependable.

The retinal vasculature is composed of the arteries and veins with their tributaries which are visible within the retinal image. The segmentation and measurement of the retinal vasculature is of primary interest in the diagnosis and treatment of a number of systemic and ophthalmologic conditions. The accurate segmentation of the retinal blood vessels is often an essential prerequisite step in the identification of retinal anatomy and pathology. In this study, we present an automated approach for blood vessels extraction using mathematical morphology. Two main steps are involved: enhancement operation is applied to the original retinal image in order to remove the noise and increase contrast of retinal blood vessels and morphology operations are employed to extract retinal blood vessels. This operation of segmentation is applied to binary image of top-hat transformation. The result was compared with other algorithms and give better results