A field experiment was carried out in one of the plastic houses belonging to the College of Agriculture, Al-Qasim green University to Studying the possibility of cultivating cucumis melo var. flexuosus inside greenhouses to improve growth and yield using microelements and ethephon. Microelements (Zn + B) at a concentration of 250 mg/L -1 and the growth regulator Elathyphon at a concentration of (2.5, 1.5, 0) ml/L -1 were used as a spray on the shoots. A factorial experiment was applied with the split plot system and randomized complete block design (RCBD) according to the least significant difference (L.S.D) test under the significance level of 0.05. The results were as follows: The interaction between (Zn + B) had a positive and significant effect on indicators such as leaf area 206.88 dm-1, number of female flowers 22.33flower-1, and the total yield 4327 kg, the percentage of nitrogen, phosphorous and potassium in the leaves was 0.6733, 2.691, 2.927, and the percentage of zinc and boron in the leaves was 19.626,14.282.The yield of one plant and the weight of the fruit 2575.5 g, 121.44 g, respectively. As for the interaction between Zn + B + 1.5, a significant effect on leaf area trait 239.91 Number of female flowers 26.33 flower-1, Total yield 5494 kg The percentage of PK in leaves 0.7233,3.080 and the percentage of boron in leaves 14.560 while the yield of one plant 3270.4 g