A477 diabetes complications are higher among older patient groups. The study ailms to systematically collate the available information on costs of major complications of type 2 diabetes in Australia, Canada, UK and USA. Methods: Published literature is searched in Medline, Embase, Cochrane, Scopus and EconLit to identify relevant English-language articles for the period 2005 to 2017. The review included studies that present monetary estimates on costs of one or more type 2 diabetes mellitus complications among adults 18 years and above. All costs are inflated to 2016 values using the health care component of consumer price indices in the respective countries and converted into 2016 international dollars (Int$) to facilitate comparability across countries, with information to enable translation into local currencies. Results: Studies on direct costs of type 2 diabetes complications, most of which were conducted from a health care payer perspective using cost data from administrative databases, were included. The annual direct medical cost of myocardial infarction associated with diabetes
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