This study was conducted to evaluate the efficacy of the biocontrol fungi Chaetomium cupreum, Trichoderma viride, and Saccharomyces cerevisiae and some chemical nutrients that stimulate plant growth, such as calcium nitrate, ammonium phosphate, aqueous magnesium sulfate, copper and boron in controlling some common soil-borne pathogenic fungi and evaluating their role in stimulating plant growth. All the bioagents showed significant antagonistic efficiency In vitro against the pathogenic fungi Drechslera Halodes, Fusarium oxysporum, Fusarium solani, Macrophomina phaseolina, Pythium aphanidermatum and Rhizoctonia solani. Under greenhouse conditions, BC treatment composed of biological and chemical elements, achieved the highest germination rate for tomato, cucumber and cowpea seeds inoculated with the pathogenic fungi, and reached 95.83-100.00% compared to 36.67- 47.50% for the control treatment. BC treatment also excelled in reducing disease incidence and severity, as the disease rate reached 0% compared to 95.83-99.17 % for the inoculated control treatment, and without significant difference with the non-inoculated (healthy) control. In addition, the BC treatment produced 0 % disease severity rate as compared to 82.58-85.83% for the inoculated control, and without significant difference with non-inoculated control. Furthermore, the BC treatment was superior to the rest of the treatments in increasing dry weight of all the plant species tested. Keywords: Chaetomium cupreum, Trichoderma viride, Saccharomyces cerevisia, Soil-borne fungi, biological control.