Background: The aim of this study is to assess the use of cable-wire construct together with bone grafting for direct repair of pars defects in spondylolysis. Patient and methods:Thirty patients with bilateral pars defect in complaining of low back pain were included in this prospective study. A cable-screw construct was used for pars repair after failure of conservative measures. Patients were assessed radiologically for union and clinically by Oswestry disability index (ODI) and VAS for back pain. Demographic data and any complications were noted. Results:The mean follow up period was 22 months. The mean preoperative ODI and VAS were 67.77 and 8.2 respectively. This improved to 11.07 and 1.33 at final follow up. The improvements were statistically significant. At the final follow up, radiological healing could be achieved bilaterally in all patients (86.6%) but four. Three of them had initial defects >3mm and 1 from 2-3mm. For the healed cases, the mean time to union was 4.7 months. Conclusion:The cable-screw construct appears to be a rigid, low profile construct with high success rates in treating pars defects both radiologically and clinically.Citation: Arafa AM, Zahlawy HE, Abdelrady AM (2017) The Use of Cable-Screw Construct as an Effective Method for Direct Pars Repair. MOJ Orthop Rheumatol 9(5): 00372.