Introduction: Cardiopulmonary resuscitation (CPR) has an effective role in reducing mortality due to respiratory and cardiac arrest and in the case of timely and accurate implementation, it can significantly save lives. Therefore, teaching and learning CPR is one of the most basic and vital skills that a person must learn in life. During the past few years, CPR and first aid in the form of simple and basic education programs have been provided for the public around the world.Objective: The purpose of this paper was discussing the latest findings in CPR. Materials and Methods: This is a review article based on the translation of the instructions of CPR in AmericanHeart Association in 2015, with an emphasis on CPR, as well as other library materials and articles written between 2010 and 2015.Results: unprofessional and professional revivalists play a vital role in restoring a person who has undergone cardiopulmonary arrest; therefore, they must be trained in CPR operations in accordance with the latest guideline updates. These changes in 2015 adults' basic life support measures and guidelines for resuscitation include correction of the algorithm with the emphasis on comprehensive simplified algorithm, based on the recommendations of CPR performance by professional and unprofessional revivalists, the use of defibrillation in cardiac arrest by the public, CPR quality, and reduction of delays as much as possible. Discussion and Conclusion:Knowledge of CPR and its latest changes is obviously necessary to all professional and unprofessional revivalists.

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