Multiple sclerosis (MS) is a disease of the central nervous system that results in many symptoms

Background:Sarcopenia describes the inevitable deterioration in muscle mass and strength that accompanies biological aging. The purpose of this study was to investigate the effects of resistance training (RT) on quadriceps hypertrophy and related biochemistry in sarcopenic and healthy elderly men.Methods:A total of 31 elderly men (55–70 years old) were classified as sarcopenic and nonsarcopenic and were divided into two groups. Both groups participated in a progressive RT program for 8 weeks.Results:Data indicated that the strength in the sarcopenic group increased more than the healthy group (P < 0.05). Quadriceps cross-sectional area also increased more in the healthy group (P < 0.05). Myostatin concentration decreased in both groups after training (P < 0.05). Follistatin and testosterone increased in the healthy group; in contrast, only testosterone increased in the sarcopenic group after training (P < 0.05).Conclusions:The findings from this study suggest that RT improves muscle cross-sectional area and biomarker-related muscle loss in both healthy and sarcopenic elderly men. The findings also demonstrate that growth factor profiles at baseline and changes in testosterone levels play an important role in muscle hypertrophy observed in both groups.

Relationship between Jump Test Results and Acceleration Phase of Sprint Performance in National and Regional 100m SprintersThe purpose of this research was to identify the relationship between jump test results and acceleration phase of sprint performance in national and regional 100m sprinters. Fifteen male (age 21.89 ± 3.26 years; body height 1.72.66 ± 3.20 m; body mass 61.35 ± 11.40 kg; 100 m personal best: 11.67 + 0.46 s {11.00 - 12.19}) track sprinters at a national and regional competitive level performed 10 m sprints from a block start. Anthropometric dimensions, along with squat jump (SJ), countermovement jump (CMJ), continuous straight legged jump (SLJ), single leg hop for distance, and single leg triple hop for distance measures of power were also tested. Pearson correlation analysis revealed the single leg hop for distance with front and back leg (respectively, r = -0.74 and r = -0.76; p = 0.021 and p = 0.017), and the single leg triple hop for distance with front and/or back leg (respectively, r = -0.84 and r = -0.89; p = 0.004 and p = 0.001), generated capabilities to be strongly related to sprint performance. Further linear regression analysis predicted an increase in the single leg hop for distance with front and back leg of 10 cm, to both resulted in a decrease of 0.07 s in 10 m sprint performance. Further, an increase in the single leg triple hop for distance with front and/or back leg of 10 cm was predicted to result in a 0.08 s reduction in 10 m sprint time. The results of this study seem to suggest that the ability to gain more distance with the single leg hop and the single leg triple hop for distance to be good indicators for predicting sprint performance over 10 m from a block start.

Background Different physical activities and diets change the regulation of inflammations in both type 2 diabetes (T2D) patients and obese individuals, but the effect of both (Physical activity and diet) on pro/anti-inflammations has remained unknown. We investigated pro/anti-inflammations control, cardiovascular function, and total physiological parameters before and after 24 weeks of low volume high intensity interval training (HIIT) on a cycle ergometer along with four dietary regimes in obesity with T2D patients. Methods 33 non-active obesity T2D patients (BMI ≥ 30) midges (47 yrs. ± 5) were volunteered to participate and randomly divided into three experimental(n = 11) [( 1) LCD = low Carbohydrate Diet, (2) LFD = Low Fat Diet and (3) HFD = High Fat Diet)] and one control (n = 9) [ND = normal diet] groups. The whole groups performed underwent 8-week dietary regimes and then performed 3 days/weeks (3 set 10 × 60 s) HIIT on a cycle ergometer for 12 weeks, which followed by a 4-week diet period again. Also, prior to and after 8 weeks diet-12 weeks High Intensity Interval Training (HIIT) and 4 weeks diet 2-h oral glucose tolerance test (OGTT), resting blood pressure, incremental maximal oxygen uptake (VO2peak) cycle ergometer test and blood sample was collected from the subjects in order to measure pro/anti-inflammatory cytokines (IL-6, TNF-α, leptin, resistin, adiponectin, and FGF21). Results After 24 weeks of intervention, the results indicated that the highest improvement in the percentage of changes in glucose happened in LCD (−34.76), insulin in ND (+16.43), cholesterol in LCD (−33.35), LDL in LFD (−9.14), HDL in LCD (+41.81), TG in LCD (−40.71), weight in LCD (−12.49) and HOMA-IR in HFD (−6.82). The results also indicated that after 24 weeks of HIIT and diet interventions, highest benefit percentage change IL-6, resistin and leptin occurred in LCD (−32.10, −28.29 and − 53.92, respectively), TNF-α, FGF21 and adiponectin in LFD (−48.06, +55.30 and + 42.32, respectively). However, these changes were observed in other groups. Conclusions These results demonstrated that HIIT along with low carbohydrate regimes improves overall cardiovascular parameters and reduce pro-inflammatory markers and increase anti-inflammatory markers in type 2 diabetic patients. Additionally, as with HIIT along with low carbohydrate, HIIT coupled with low fat would improve inflammation markers, though these effects were less significant. These findings suggest that HIIT along with low carbohydrate is a beneficial exercise and dietary strategy in T2D patients.

Background Performing exercise with medium intensity has positive effects on the maternal health. The aim of this study was to investigate the effectiveness of Pilates exercise program during pregnancy on childbirth outcomes: Methods This clinical trial study was performed on 110 primiparous women who were randomly divided into two groups of intervention (n = 55) and control (n = 55). The intervention group performed Pilates exercises from 26 to 28 weeks of gestation for 8 weeks while the control group did not do any exercise. Data collection tools included Visual Analog Scale (VAS), Mackey Childbirth Satisfaction Rating Scale, and a checklist including demographic and obstetrics information. Results The results of the study showed that Pilates exercise during pregnancy significantly reduces the labor pain intensity, length of the active phase and second stage of labor and increases maternal satisfaction of the labor process (p < 0.05). Based on the Kaplan Meyer analysis, the mean whole length of labor was shorter in Pilates exercise group than in the control group (P = .004). There was no statistically significant difference between the two groups in terms of Episiotomy, type of delivery, first and fifth Apgar score of neonates (p > 0.05). Conclusion According to the results of this study, Pilates exercise during pregnancy improved the labor process and increased maternal satisfaction of chidbirthprocess, without causing complications for the mother and baby. However, studies with larger sample sizes are recommended to prove the efficacy and safty of this practiceduring labor. Trial registration IRCT registration number:IRCT20200126046266N1. Registration date: 2020-05-02 (retrospectively registered).