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Background:It has been shown that inflammation and insufficient blood vessel formation delay wound healing, whereas Boswellia serrata, besides anti-inflammatory activity, increases blood vessel formation. Objectives: This study was performed to investigate the effect of Boswellia serrata in promoting burn injuries healing in BALB/c mice. Materials and Methods:In this experimental study, a burn wound was created by placing a 1.5 cm 2 hot plate on the back of animals. Fifty four mice were designated in four equal groups, counting 14 each. Three groups of animals were treated with Boswellia 2%, silver sulfadiazine and vaseline two times per day for 21 days. The fourth group represented the control group. The total percentage of wound healing and time required for complete healing were evaluated and compared between groups, using the ANOVA test. Results: Results showed that the effect of Boswellia on wound healing was statistically significant compared to the control group (P < 0.01). Conclusions: Boswellia serrata is clearly effective for burn injuries healing and might be used in patients with burn wound.

In a survey of 430 Lori-Bakhtiari sheep at a slaughterhouse in Iran, gallstones were found in the gallbladder of 7 sheep (1.6%). Biliary calculi were more frequent in adult and female sheep (P < 0.05). Chemical analysis of the gallstones revealed 6 sheep with pigment (bilirubin) stones and 1 sheep with cholesterol stones. Chemical composition of bile in these sheep was evaluated. Bacteriologic analysis of the bile in the affected sheep revealed bacteria (Streptococcus spp., Klebsiella spp., Escherichia coli, and Salmonella spp.) in 5 sheep. Microscopic examination of gallbladders revealed focal calcification, cystic glands, necrosis and atrophy of mucosal layer, edema, diffuse and focal infiltration of lymphocytes in submucosal layer, and hypertrophy of smooth muscles in sheep with gallstones. It was concluded that the prevalence of both types of gallstones in Lori-Bakhtiari sheep is low. Cholelithiasis can cause chronic inflammation of the gallbladder, but it is not likely to become clinically significant.