Genus Sargassum termasuk kelas rumput laut cokelat (Phaeophyceae) yang terdiri dari sekitar 400 spesies, dan banyak ditemukan di perairan Indonesia. Sargassum sp. kaya dengan berbagai jenis senyawa bioaktif, yang penting untuk pencegahan maupun terapi berbagai penyakit. Ulasan ilmiah ini dilakukan untuk mengulas jenis-jenis senyawa bioaktif, senyawa bioaktif dominan, dan aktivitas biologisnya dalam genus Sargassum, berdasarkan penelitianpenelitian ilmiah yang telah dipublikasikan. Dari ulasan ilmiah ini dapat diketahui bahwa senyawa-senyawa bioaktif dalam Sargassum sp. meliputi florotanin, terpenoid, chromene, derivat tetraprenyltoluquinol, fukosantin, fukoidan, alginat, asam-asam fenolat, katekin, kuersetin, fukosterol, stigmasterol, β-sitosterol, feofitin A, dan sulfoquinovosyldiacylglycerol. Florotanin, fukosantin, fukoidan, alginat, fukosterol, meroditerpenoid dan gentisic acid adalah senyawa bioaktif dominan dalam Sargassum sp. Meroditerpenoid merupakan senyawa bioaktif khas dalam Sargassum sp., yang tidak diproduksi oleh genus rumput laut lainnya. Aktivitas biologis dari senyawa-senyawa bioaktif Sargassum sp. yaitu antioksidan, antikanker, antitumor, antiinflamasi, antihipertensi, antiobesitas, antidiabetes, antibakteri, antifungi, antivirus, antialergi (ovalbumin dan udang), hipokolesterolemia, neuroprotektif, pencerah kulit dan proteksi ROS intraseluler. Dengan demikian, senyawa-senyawa bioaktif dalam Sargassum sp. potensial untuk mendorong kesehatan

Background: S. cristaefolium is the brown seaweed extracted using the serial technique with different solvents. Methods: S. cristaefolium powder (50 mesh) was extracted with hexane, ethyl acetate, and methanol respectively. The S. cristaefolium powder residue had been dried before being re-extracted with the next different solvents. Three serial extracts were obtained and named as the 1-stage extract, 2-stage extract, and 3-stage extract. Besides, a single-step extract (extraction using only methanol) was also produced to compare with three serial extracts in antibacterial activity tests (against E. coli and S. aureus). The three serial extracts were detected their antibacterial compounds using GC-MS, LC-HRMS, and FT-IR. Results: The 3-stage extract had the highest extraction yield. On S. aureus, the inhibition zone in all extracts was not significantly different. On E.coli, the highest inhibition zone (5.42±0.14 mm) was the 3-stage extract, indeed it is higher than both antibiotic and a single-step extract. Phenol, 9-Tricosene(Z)-, palmitic acid, and oleamide were contained in all extracts. Other antibacterial compound types, both the 1-stage and 2-stage extracts contained 8 types whilst the 3-stage extract contained the most types (12 types). Particularly, hexyl cinnamic aldehyde and betaine were detected only in the 3-stage extract with the dominant area. The carboxylic acid groups were detected in all extracts to confirm the fatty acid structure. Several cinnamic aldehyde groups were detected only in the 3-stage extract. Conclusions: Thus, the extraction technique serially could produce the 3-stage extract which has the strongest antibacterial activity and the richest antibacterial compounds.

A commercial herbal oil with different bottle materials on the Indonesian markets was studied. The effects of the different specimens viz. PET-new, PET-open, and AL-new on the main antibacterial components of herbal oil were investigated.Step-1, analysis of antibacterial activity (against S. aureus and E. coli) and testing of non-toxic (in-vivo).Step-2, detection of the main antibacterial compounds (6 types) during the storage times. The market and environmental aspects were also considered. The results, all specimens had antibacterial activity and they showed non-toxic. At the 0-month, six types of main antibacterial compounds were detected in all specimens. The longer the storage time, the more main antibacterial compounds were lost. The most loss (4 types) was observed in and PET-open. PET-new showed the least loss (1 type) at 6-months and 12-months, namely eugenol. Interestingly, PET-new was able to retain curcumene, farnesol, and p-cymene for up to 12 months of storage. PET-new was also more economical (8.7% cheaper) and environmental-friendly than AL-new. The sprayer cap types are strongly recommended for PET herbal oil packaging.

Melinjo tree is a tree that is commonly found in Cilayang Village, Cikeusal District. Melinjo has many benefits, the wood can be used as a simple board and household appliance, the young leaves are referred to as so in Javanese used as vegetable ingredients, for example in the vegetable asem flowers and seeds that are still small or that have been cooked are also used as vegetables, melinjo seeds are also used as raw materials for emping, and the skin can be used as a vegetable. To improve the economy of the people of Cilayang Village, especially for housewives, it is necessary to have innovation from this melinjo. The implementation of this community service activity is in the form of assistance for EMPING MSMEs in Cilayang Village. The innovation carried out from emping is by creating a press machine to facilitate the production process, variations in emping flavors with four flavors, namely original, salty, pedaas, and original. As well as the packaging of empings that are packaged to be more modern.  As a result of this activity, the people of Cilayang Village are able to produce light food from melinjo fruit