Mediastinal masses in children comprises of a heterogeneous group of tumours. In such cases, biopsy and histological analysis are mandatory for planning of treatment. We have reported an unusual aetiology for a mediastinal mass in a young boy presenting with features of Superior Vena Caval Obstruction (SVCO) who also had marked blood and marrow eosinophilia mimicking Chronic Eosinophilic Leukaemia (CEL). We have also discussed the differential diagnoses of mediastinal tumours with hyper-eosinophilia and possible therapeutic implications.

BACKGROUNDAccumulating evidence suggests that Helicobacter pylori (H. Pylori) infection account for many unexplained cases of Iron Deficiency Anaemia (IDA), which may benefit from testing and treatment for H. pylori infection. This study attempts to evaluate the role of anti H. pylori treatment in management of iron deficiency anaemia among patients treated at a tertiary care centre in North India. MATERIALS AND METHODSThis was a prospective study which included 60 patients with IDA, proven positive for H. pylori by Rapid urease test and histopathological staining. They were divided into three groups (n= 20) and received different treatments, i.e. only anti-H. pylori therapy/ oral iron therapy plus anti-H. pylori therapy/ only oral iron therapy. Haemoglobin, RBC indices, Reti count, S. iron and S. ferritin were compared at the end of treatment with One-Way ANOVA.