Objective: To estimate the Primary Hypothyroidism and to study its effects on the Quality of Life of those patients. Study design: It was a Cross-Sectional Study done using random sampling. Sample size: 463 patients Duration and location of the study: It was done between December 2018 and December 2019 in outpatient clinics of a tertiary care hospital in Riyadh. Study tool: The quality of life of these patients was assessed by World Health Organization (WHO) Health Survey 36-Item Short Form (SF-36) questionnaire with a score less than 50% was considered to be ‘Poor quality’. Results: The response rate of participants was 92.6% and the prevalence of Primary Hypothyroidism was observed to be 47.8%. They experienced a poor mental health with an average score (35.1 ± 1.6). Factors such as illiteracy (35.0 ±1.0), primary level of education (29.4 ± 3.6), housewife (43.49 ± 38.19) and the retired patients (20.31 ± 37.88) had a poor Physical function (P=0.001). However, the patients without primary hypothyroidism had better quality of life with physical, social and mental functional scores (P=0.001). The statistically significant poor quality of life observed due to poor education, income level and marital status exposed the need for the guidelines and management of this morbidity in the Saudi community. Keywords: Primary Hypothyroidism, SF-36, Quality of Life, Cross-Sectional study

Background: bronchial asthma is a long-standing disease which results from airway inflammation and hyper responsiveness. Methodology: this is a crosssectional study which was conducted in Riyadh, Saudi Arabia. It included 175 participants, using a convenient sampling technique. A Self-administered, precoded, and pre-tested questionnaire was used. The collected data was reviewed and statistically analyzed by using SPSS version 23 and P=Value of 0.05 or less is considered significant. Results: 66.3% of participants were females, and majority of the participants were in the age group of 18-30. 58.3% of participants had a moderate level of awareness regarding bronchial asthma.It also showed that 46.3% had moderate levels and 44.6% had high-level regarding triggering factors. 60% and 54.3% had high levels regarding complications and symptoms respectively. Only 21.7% of respondents were asthmatic. Conclusion: most of the responses showed moderate level of awareness regarding bronchial asthma. There was a significant statistical relationship between gender and the level of awareness regarding complications of bronchial asthma, and the relation between male and female regarding symptoms of bronchial asthma.

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