ObjectivesTo investigate the optical coherence tomography angiography (OCTA) and specular microscopy (SM) findings in obese children and compare them with healthy ones.MethodsIn this prospective study, 50 eyes of 25 obese children [body mass index (BMI) ≥95th percentile], 36 eyes of 18 control age- and sex- matched healthy subjects (BMI <85th percentile) were included. Demographic features and ophthalmological examination including OCTA measurements as well as SM findings were assessed. Cellular morphology was observed by noncontact SM and results for corneal endothelial cell density (cells/mm2), coefficient of variation of cell size and percentage of hexagonal cells were obtained. The OCTA was performed with 6 × 6 mm sections for macula and 4.5 × 4.5 mm sections for optic disc in all eyes. Foveal retinal thickness (FRT), retinal nerve fiber layer (RNFL) thickness, vessel density in different sections of retina and optic nerve head were analyzed.ResultsAll SM parameters, RNFL thickness for average, and all quadrants and optic disc radial peripapillary capillary densities were similar between groups. However, FRT, flow area for choriocapillaris, superficial and deep foveal capillary densities were significantly higher in obese group when compared to controls (242.4 ± 18.2 µm vs. 232.1 ± 16.5 µm, p=0.024, 2.2 ± 0.1 mm2 vs, 2.2 ± 0.0 mm2, p=0.042, 22.4 ± 6.9% vs. 15.6 ± 5.5%, p=0.001, and 38.9 ± 7.5% vs. 31.1 ± 8.6 %, p=0.001, respectively).ConclusionsObese children seem to have higher values of FRT, flow area for choriocapillaris, superficial and deep foveal capillary densities. These results may have significant implications for understanding of how childhood obesity could affect retinal microvasculature.
To investigate the optic disc and retinal microvasculature by optical coherence tomography angiography (OCTA) in children with asthma and compare them with healthy ones. MethodsSixty eyes of 30 asthmatic children (asthma group), 60 eyes of 30 control age-and sex-matched healthy subjects (control group) were included to this study, prospectively. Demographic features and ophthalmological examination including OCTA measurements were evaluated. The OCTA was performed with 6x6 mm sections for macula and 4.5x4.5 mm sections for optic disc in all eyes. Retinal nerve ber layer (RNFL) thickness, vessel density in different sections of retina, and optic nerve head were analyzed. ResultsRNFL thickness for temporal quadrants and ow area for outer retina levels were signi cantly lower in asthma group. However, inside disc densities were signi cantly higher in asthma group when compared to controls (72.58±10.99µm vs 77.73±9.73µm, p = 0.015, 0.60 ± 0.31mm 2 vs 0.72 ± 0.31mm 2 , p = 0.047, and 55.16 ± 3.71% vs 52.08 ± 3.79%, p < 0.001, respectively). ConclusionsAsthmatic children seem to have lower values of temporal quadrant RNFL, and ow area for outer retina, but higher levels of inside disc density. These results may have signi cant implications for understanding of how asthma could affect retinal microvasculature.
Introduction: Schnyder corneal dystrophy (SCD) is a rare, autosomal dominant, anterior stromal dystrophy described as progressive bilateral corneal opacification due to abnormal accumulation of cholesterol and phospholipids in the cornea. The clinical signs can change as the patient ages. SCD with different presentations may actually be misdiagnosed. Early diagnosis would help to rule out other potentially sight threatening or treatable conditions like infectious keratitis or drug toxicity. Case: We present a case of a 34-year-old Syrian male patient, came to our clinic for bilateral decreased visual acuity for 5 years. His visual acuity was 0.15 in both eyes. Slitlamp examination revealed corneal arcus or disk-like lesion and polychromatic crystalline depositions in both eyes in subepithelial and the anterior 1/3 of the stroma. The mild onset of arcus lipoides was also seen. Central corneal thickness results were 507 μm in the right eye and 503 μm in the left eye. A diagnosis of Schnyder corneal dystrophy was thought based on clinical presentation and coexistence dyslipidemia of the patient. Conclusion: Ophthalmologists should keep in mind SCD and its associated systemic findings that need to be evaluated and managed properly.
Purpose To investigate the optic disc and retinal microvasculature by optical coherence tomography angiography (OCTA) in children with asthma and compare them with healthy ones. Methods Sixty eyes of 30 asthmatic children (asthma group), 60 eyes of 30 control age- and sex- matched healthy subjects (control group) were included to this study, prospectively. Demographic features and ophthalmological examination including OCTA measurements were evaluated. The OCTA was performed with 6x6 mm sections for macula and 4.5x4.5 mm sections for optic disc in all eyes. Retinal nerve fiber layer (RNFL) thickness, vessel density in different sections of retina, and optic nerve head were analyzed. Results RNFL thickness for temporal quadrants and flow area for outer retina levels were significantly lower in asthma group. However, inside disc densities were significantly higher in asthma group when compared to controls (72.58±10.99µm vs 77.73±9.73µm, p = 0.015, 0.60 ± 0.31mm2 vs 0.72 ± 0.31mm2, p = 0.047, and 55.16 ± 3.71% vs 52.08 ± 3.79%, p < 0.001, respectively). Conclusions Asthmatic children seem to have lower values of temporal quadrant RNFL, and flow area for outer retina, but higher levels of inside disc density. These results may have significant implications for understanding of how asthma could affect retinal microvasculature.
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