Robots are becoming an integral component of our society and have great potential in being utilized as an educational technology. To promote a deeper understanding of the area, we present a review of the field of robots in education. Several prior ventures in the area are discussed (post-2000) with the help of classification criteria. The dissecting criteria include domain of the learning activity, location of the activity, the role of the robot, types of robots and types of robotic behaviour. Our overview shows that robots are primarily used to provide language, science or technology education and that a robot can take on the role of a tutor, tool or peer in the learning activity. We also present open questions and challenges in the field that emerged from the overview. The results from our overview are of interest to not only researchers in the field of human-robot interaction but also administration in educational institutes who wish to understand the wider implications of adopting robots in education.
BACKGROUNDCauses of early infant growth restriction remain incompletely understood. Where vitamin D deficiency is common, vitamin D supplementation during pregnancy and lactation may improve fetal-infant growth and other birth outcomes.METHODSWe conducted a randomized, double-blind, placebo-controlled trial of maternal vitamin D supplementation from 17-24 weeks gestation until birth or 6 months postpartum. Participants were randomly allocated to five vitamin D and/or placebo supplementation groups: (A) 0 IU/week, (B) 4200 IU/week, (C) 16800 IU/week, or (D) 28000 IU/week in pregnancy, all with 0 IU/week postpartum; or, (E) 28000 IU/week in prenatal and postpartum periods. The primary outcome was length-for-age z-score at one year of age according to World Health Organization child growth standards.RESULTSAmong 1164 infants assessed at one year of age (90% of 1300 pregnancies), there were no differences across groups in length-for-age z-scores (mean ±standard deviation): A: -0.93 ±1.05, B: -1.11 ±1.12, C: -0.97 ±0.97, D: -1.06 ±1.07, E: -0.94 ±1.00 (p=0.23). Groups were similar with respect to other anthropometric measures, birth outcomes, and morbidity. Vitamin D had dose- dependent effects on maternal and infant serum 25-hydroxyvitamin D and calcium, maternal urinary calcium excretion, and maternal parathyroid hormone concentrations. No clinical adverse events were attributed to the vitamin D intervention. CONCLUSIONSIn a population with widespread prenatal vitamin D deficiency and fetal/infant growth restriction, maternal vitamin D supplementation from mid-pregnancy until birth or 6 months postpartum does not influence fetal or infant growth, and has no beneficial or harmful effects on numerous other birth and infant outcomes.
BackgroundAntenatal vitamin D status may be associated with the risk of adverse pregnancy and neonatal outcomes; however, the benefits of vitamin D supplementation during pregnancy remain unknown.MethodsWe conducted a double-blind placebo-controlled randomized trial to evaluate the effect of high-dose prenatal 3rd trimester vitamin D3 supplementation on maternal and neonatal (cord blood) serum 25-hydroxyvitamin D (25(OH)D) concentration (primary biochemical efficacy outcome) and maternal serum calcium concentration (primary safety measure). Eligibility criteria were pregnant women aged 18 to <35 years, at 26 to 29 weeks gestation, and residing in Dhaka, Bangladesh. 160 women were randomized by 1:1 allocation to one of two parallel intervention groups; placebo (n = 80) or 35,000 IU/week of vitamin D3 (n = 80) until delivery. All participants, study personnel and study investigators were blind to treatment allocation.ResultsMean maternal 25(OH)D concentration was similar in the vitamin D and placebo groups at baseline (45 vs. 44 nmol/L; p = 0.66), but was significantly higher in the vitamin D group vs. placebo group among mothers at delivery (134 vs. 38 nmol/L; p < 0.001) and newborns (cord blood: 103 vs. 39; p < 0.001). In the vitamin D group, 95% of neonates and 100% of mothers attained 25(OH)D >50 nmol/L, versus 21% mothers and 19% of neonates in the placebo group. No participants met criteria for hypercalcemia, there were no known supplement-related adverse events, and major pregnancy outcomes were similar between groups.ConclusionsAntenatal 3rd-trimester vitamin D3 supplementation (35,000 IU/week) significantly raised maternal and cord serum 25(OH)D concentrations above 50 nmol/L in almost all participants without inducing hypercalcemia or other observed safety concerns. Doses up to 35,000 IU/week may be cautiously used in further research aimed at establishing the clinical effects and safety of vitamin D3 supplementation in pregnancy.Trial registrationThis trial was registered at ClinicalTrials.gov (NCT01126528).
Climate change is expected to increase global mean temperatures leading to higher tropospheric ozone (O3) concentrations in already polluted regions, potentially eroding the benefits of expensive emission controls. The magnitude of the “O3-climate penalty” has generally decreased over the past three decades which makes future predictions for climate impacts on air quality uncertain. Researchers attribute historical reductions in the O3-climate penalty to reductions in NOx emissions, but have so far not extended this theory into a quantitative prediction for future effects. Here we show that a three-dimensional air quality model can be used to map the behavior of the O3-climate penalty under varying NOx and VOC emissions in both NOx-limited and NOx-saturated conditions in Central and Southern California, respectively. Simulations suggest that the planned emissions control program for O3 precursors will not diminish the O3-climate penalty to zero as some observational studies might imply. The results further demonstrate that in a NOx-limited air basin, NOx control strategies alone are sufficient to both decrease the O3-climate penalty and mitigate O3 pollution, while in a NOx-saturated air basin, a modified emissions control plan that carefully chooses reductions in both NOx and VOC emissions may be necessary to eliminate the O3-climate penalty while simultaneously reducing base case O3 concentrations to desired levels. Additional modeling is needed to determine the behavior of the O3-climate penalty as NOx and VOC emissions evolve in other regions.
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