IntroductionA ventral hernia is defined as a non-inguinal, non-hiatal defect in the fascia of the abdominal wall. Approximately 350,000 ventral hernia procedures are performed each year. Ventral hernia can have a negative impact on a person's quality of life and, in severe situations, lead to hospitalization and even death. AimThis study aimed to assess the knowledge of the general population living in the Al-Ahsa region regarding the risk factors of ventral hernia. Subjects and methodsThis is a cross-sectional study conducted among the general population living in the Al-Ahsa region of Saudi Arabia. A self-administered questionnaire was distributed among the population using an online platform. The questionnaire includes basic demographic characteristics (age, gender, and body mass index (BMI)) and a nine-item questionnaire to assess the knowledge of risk factors of ventral hernia. ResultsOf the 803 respondents involved, 42.1% were aged between 22 and 28 years old, and 44.4% were either overweight or obese. According to participants' knowledge, the most common risk factor of ventral hernia was heavy weight lifting (87.4%), and pregnancy and labor (64.1%). The overall mean knowledge score was 5.78 (standard deviation (SD): 2.68) out of 12 points. Nearly half (49.4%) were considered to have poor knowledge levels, 40.2% were considered to have moderate knowledge levels, and only 10.6% were considered to have good knowledge levels. Increased knowledge was seen more frequently in younger participants, males, and respondents with normal or underweight BMI. ConclusionThe knowledge of the general population regarding the risk factors of ventral hernia was insufficient. Of all the population, male respondents who were younger and had a normal body mass index demonstrated a better understanding of the ventral hernia's risk factors compared to the rest of the subjects. Further research is needed to establish the knowledge of the general population regarding the risk factors of ventral hernia in our region.