Introduction: Tooth loss is a worldwide public health concern of huge proportion. Problems associated with permanent tooth loss are enormous. Aim: This study aims to investigate the major reasons and patterns of permanent tooth extraction in a government referral dental center. Materials and Methods: This retrospective study was conducted on patients who had intra-alveolar extraction of teeth in our facility between January 2016 and December 2020. Sociodemographic data and type of tooth extracted were recorded. Reasons for extraction were classified into the following: caries, failed root canal treatment, failed restoration, periodontitis, prosthodontic, orthodontic, trauma, and over-eruption. Data were stored and analyzed with SPSS for MOS, Version 20.0. Results and Discussion: A total of 8065 (3248, 0.3%) males and 4817 (59.3%, females) patients presented for teeth extraction during the study period with 11,746 extractions done, giving an average of 1.5 extractions per individual. The age range of 11–102 years with a mean (±standard deviation) of 36.0 (16.6) was observed. The majority of the patients were in the age groups of 21–30 years (1992 (24.7%), then 31–40 years (1773 (22.0%). Caries and its sequelae accounted for the main reasons for tooth mortality. In the mandible, a total of 5321 (45.3%), while in the maxilla, a total of 6425 (54.7%) teeth were extracted. Molars were the most extracted tooth in both jaws (3485 (29.7%)) Conclusions: The current study found that dental caries, and its sequelae, was the main reason for tooth extraction in a Saudi subpopulation, Najran. Molars were the most commonly extracted teeth.

Platelet-rich plasma (PRP) has been reported as an efficacious modality that can enhance the process of wound healing and tissue regeneration and has been validated in different medical settings, including cardiovascular surgery, otolaryngology, head and neck surgery, and maxillofacial surgery. In dental and oral surgery settings, PRP has been reported as an efficacious approach with favorable outcomes in different settings. Some of these procedures include surgical repair of the alveolar cleft, mandibular reconstruction, ablative surgical procedures, placement of osseointegrated implants, periodontal plastic surgery, and management of infrabony periodontal defects. In the present study, we aim to discuss the role and mechanisms that PRP plays in the settings of maxillofacial surgery based on evidence from the relevant studies in the literature. Evidence indicates the wide acceptance of the modality, which has been proven to increase the rate of wound healing and reduce the frequency of pain and swelling. The administration of PRP has been reported to dispense with the need for invasive approaches that might be furtherly associated with complications and different morbidities. However, in most of the favorable events where the PRP administration of was associated with enhanced outcomes, the modality was used in combination with another therapeutic approach. Therefore, further research is needed to validate the efficacy of the modality in the different settings.