Middle East Technical University – Defocusing Beam Line (METU-DBL) project is an irradiation facility providing 15 MeV to 30 MeV kinetic energy protons for testing various high radiation level applications, ranging from Hi-Lumi LHC upgrade, space electronic components to nuclear material research. The project located inside the premises of the TAEA (Turkish Atomic Energy Agency) SANAEM (Saraykoy Nuclear Education and Research Center) close to Ankara, provides users a wide selectable flux menu (105–1010 p/cm2/s). The facility is now being commissioned and the facility will be providing a large test area (20 cm x 15 cm) for material, detector and electronics tests. The proton beam is monitored along the beamline using aluminum oxide screens and the flux and uniformity is measured using three detectors attached to the robotic system for cross- checks. A fiber scintillator detector scans the large irradiation area while small area diamond detector and Timepix3 detector are used for spot checks for calibration. Several samples can be radiated simultaneously inside the irradiation area and the robotic system provides 5 separate holders for samples which can be moved in or out, providing users flexibility for the desired fluence. This talk will first introduce METU- DBL as a radiation test facility, then discuss the radiation monitoring of the beam area and the radiation room, while highlighting how this facility can be used for future testing of materials for radiation tolerance.

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A compact radiation monitor which incorporates a Geiger-Müller counter and two silicon detectors was designed and tested for radiation measurements on Turkish space rockets. The large area silicon PIN detectors, each with 4 quadrants produced in Turkey by TÜBİTAK BİLGEM UEKAE YİTAL laboratories, vertically aligned inside a thin aluminum shielding, separated by 3 PCBs as degraders, to perform coincidence logic and energy discrimination. Each quadrant is amplified separately to reduce the noise on readout cards designed by METU The Research and Application Center for Space and Accelerator Technologies (İVMER) which generate logical signals per layer, which are then coincided in a 7.8ns time window by an FPGA. The prototype also incorporates a Geiger-Müller tube sensitive to electrons and gammas to compare the counts of particles outside the box measured during test period. The I-V and C-V characterization of the PIN diodes, as well as detailed calibration of the readout electronics were performed. The device was tested at the METU-DBL (METU Defocusing Beam Line) proton beam line with 15 and 30 MeV proton beams as well as radioactive alpha and beta sources and shown to be sensitive to different particle species. The dynamic range, which has been demonstrated up to 10 6 particles/second lays the foundation for a robust radiation measurement with more detector and degrader layers for a larger energy range on a satellite over the South Atlantic Anomaly as well as van Allen belts.

The pro-apoptotic effect of new 2-thioxo-4-thiazolidinone derivative Les-3331 on MCF-7 and MDA-MB-231 cell lines ..

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