Background: Obesity and increased body mass index (BMI) are increasing among Saudi women across the all age groups, with an overall prevalence of 44%. Increased BMI is associated with advanced stage breast cancer and dismal survival; however impact of BMI on locoregional control (LRC) is less studied. We aimed to evaluate the impact of BMI on LRC in Saudi patients with breast cancer after breast conserving surgery (BCS) and modified radical mastectomy (MRM). Others factors associated with poor LRC were; age less than 40 years, premenopausal status, and no adjuvant radiotherapy, and T4, N2 and N3 stages. Conclusion: Overweight and obese patients had better locoregional control in our study, however further larger trials are warranted. Materials and methods: