Background: Even though some adverse drug reactions are minor and can be resolved quickly, some can cause permanent disability or death. Inadequate knowledge of adverse drug reactions by Nurses is a common problem of any pharmacovigilence programs. Objective: The objective of this study is to assess predictors of Nurses knowledge related to adverse drug reaction reporting at

Abstract:Background: Prevention, monitoring and reporting of adverse drug reactions is still a challenge among Nurses.Objective: to assess predictors of Nurses' practice related to adverse drug reaction reporting at Felegehiwot Referral Hospital and University of Gondar Teaching Hospital, Northwest Ethiopia. Method: Hospital based cross sectional study was conducted at Felegehiwot Referral Hospital and University of Gondar Teaching Hospital from March 11, 2013 to April 12, 2013. A total number of 214 Nurses involved in this study. Self-administered pre-tested questionnaire was used. Stratified random sampling technique was used to select study participants. Bivariate analysis and multivariable logistic regression analyses were employed for identifying not reporting practice regarding adverse drug reaction. Results: Mean age of the respondents 21.8 years (SD = 7.01). One hundred twenty two (57.0%) of the respondents were females, 152(71.7%) participants' level of education were bachelor of Nurse. The participants mean of experience were 1.64 (SD = 4.7) years. Participants who took training/seminar on Pharmacovigilance had 0.29 times more likely to have adequate knowledge (AOR = 0.29, 95% CI = 0.226-0.004, P=0.001) Conclusions and recommendation: Even though most Nurses had encountered adverse drug reaction, most of them were not reporting regarding adverse drug reaction. So Food, Medicine, Health Care Administration and Control Authority of Ethiopia should prepare training and continual education related to adverse drug reaction reporting for Nurses.