Our data suggest that tubercular involvement of rectum, although uncommon, is an important cause of rectal strictures in India. Response to antitubercular chemotherapy is uniformly good, and surgery is seldom required in these patients.

In this report, we describe this rare occurrence in a 66-year-old lady and highlight the diagnostic difficulties such cases can pose along with a review of relevant literature.

Seven cases of colorectal (five of colonic and two of rectal) tuberculosis are presented. Only one of these patients had associated pulmonary tuberculosis. Radiologic signs of colorectal tuberculosis are nontypical, making the preoperative diagnosis difficult. All five patients with colonic tuberculosis presented with subacute intestinal obstruction and underwent resectional surgery followed by antitubercular chemotherapy. Both patients with rectal tuberculosis presented with rectal strictures and were treated by repeated dilatation combined with antitubercular drugs. All seven patients have been followed for two to ten years and have remained asymptomatic.

The impact and clinical spectrum of COVID-19 infection in liver transplant recipients/solid organ transplants are being unveiled during this recent pandemic. The clinical experience of use of current antiviral drugs and immunomodulators are sparse in solid organ transplantation. We present the clinical course of a 49-year-old male recipient who underwent living donor liver transplant for recurrent gastrointestinal bleed and contracted severe COVID-19 pneumonia during the third postoperative week. Herein we report the successful management of severe COVID-19 pneumonia using convalescent plasma therapy and remdesivir. Recipient's clinical deterioration was halted after three consecutive convalescent plasma transfusions with improvement in hypoxia and inflammatory markers (interleukin-6 and C-reactive protein). The use of convalescent plasma therapy along with remdesivir may be an ideal combination in the management of severe COVID-19 pneumonia in solid organ transplant recipients.

No abstract