Immunomodulatory treatment is more often than not required beneath the conditions of impeded safe responsiveness and when the resistance components of have got to be actuated. In spite of the fact that customary immunomodulatory chemotherapy is accessible but it is so costly that it isn't more often than not reasonable to standard individuals with the socio-economic status. Subsequently, the balance of safe framework by conventional restorative plant items has gotten to be a subject matter for current logical examinations around the world. Night blossoming jasmine, botanically known as Cestrum nocturnum is an evergreen shrub that grows in tropical and sub-tropical locales all through the world. Cestrum nocturnum could be a most widespread plant due to its scent from the white blossoms. It is additionally developed as a therapeutic plant. The therapeutic properties of night sprouting jasmine incorporate antioxidant, anti-hyperlipidaemic, hepatoprotective, pain relieving, antibacterial, antifungal, anti-convulsant, anti-HIV and larvicidal exercises. The present paper reviews the immunomodulatory activity of the plant.

Biotin, a vitamin that is water-soluble, is part of the vitamin B complex and is required by all living things, including humans. Biotin-dependent carboxylases are a prosthetic group of enzymes, and biotin catalyzes essential processes in the production of fatty acids, the breakdown of amino acids, and gluconeogenesis in eukaryotic cells. The role of biotin as the prosthetic group of the four biotin-dependent carboxylases is well understood in higher animals. Based on the roles of these carboxylases in metabolism, it was discovered that biotin is required for cell survival, proliferation, and differentiation. Biotin appears to play a role in cell function and has a spermatogenic impact. Biotin has been found to have a direct impact on the transcription of important enzymes in glucose metabolism. Glucokinase and phosphoenolpyruvate carboxykinase are glycolytic enzymes that biotin controls (PEPCK). Biotin appears to be involved in gene control, which may explain some of its functions regarding fetal development and cellular biology. According to investigations using microarrays as well as other types of gene expression, biotin appears to affect the transcription of genes encoding cytokines and their receptors, glucose metabolism genes, and genes involved in cellular biotin homeostasis. A biotin shortage has a considerable effect on gene expression in numerous tissues and cells, according to a microarray study. Biotin supplementation affects the expression of several genes depending on the tissue, demonstrating that gene expression differences reflect tissue function. Biotin affects energy, lipid, and glucose metabolism, according to metabolite research, which has improved our understanding of the biotin metabolic pathway. Using microarray and transcriptome analysis, this research investigates the effect of biotin on gene expression.

The quality and quantity of health infrastructure are essential elements for the overall human development of a nation. But as per the report of WHO & World Bank (2017), at least half of the world’s population cannot obtain essential health services. Keeping in mind the above-mentioned notation, the present study focuses on the spatio-temporal disparities in healthcare infrastructure among fifty-four blocks under the undivided Medinipur district, by computing Health Infrastructure Index (HII) on the basis of thirteen selected indicators using the Deprivation Index Method, for two temporal scales i.e. for the year 2001 and 2011. The study found that there exists inter-block disparity within the region regarding the availability and accessibility of basic healthcare infrastructure with respect to the population pressure of that region. The study argued for policy implementation by the local government for improving the underdeveloped pockets within the study area.

To explore and estimate the frequency of medication error, a study conducted in a tertiary care teaching hospital of East India. The medication error can be divided into Prescribing errors, Dispatching Error, Drug Administration Errors, and Indenting Errors. The purpose of this study is to determine the prevalence and nature of medication errors; to explore the causes and to study corrective actions for such medication error. Identifying and evaluating the failures of medication errors and its severity analysis in a Tertiary care teaching hospital, Kolkata and suggesting solutions on reducing medication errors. It is a prospective study of patients receiving medication during treatment. The techniques that were used to identify the medication errors the study was carried out in a Tertiary Care 320 bedded Teaching hospital at Kolkata. Data was taken from Medication Error reporting form and medicine card of patients. Proper monitoring and capturing of medication error data has been initiated. Staff has been counselled and sensitized regarding safe medication practices and proper reporting of medication errors. Regular training on medication error has been conducted by Clinical Pharmacy Department, which improve the knowledge of monitoring, capturing, reporting and prevention of medication errors by the physicians, nurses, and clinical pharmacist. Key words: Medication errors, Administration errors, Medication Safety, Adverse drug reaction, Dispensing Error, Prescription Error