Antibiotics
are the most important drugs for people and animals
to fight bacterial illnesses. Overuse of antibiotics has had unintended
consequences, such as antibiotic resistance and ecosystem eradication
owing to toxic chemical discharge, which have a negative influence
on the biome. Herein, we report the synthesis of a hollow ellipsoid-shaped
yttrium vanadate/graphitic carbon nitride (YVO4@CN) nanocomposite
by a hydrothermal approach followed by a sonochemical method for the
effective detection of dimetridazole (DMZ). The synergic and coupling
effect between both the phases offer non-linear cumulative ramifications
which can positively enhance the individual properties of the materials
under consideration. This positive hybrid effect increases the conductivity,
shortens the ion-diffusion pathway, enhances the electron/ion transportation,
and provides more active sites and electron-conducting channels. The
accurate optimization of the experimental conditions proposes good
electrocatalytic activity for the YVO4@CN catalyst, exhibiting
a good response toward DMZ detection. It reveals an extensive linear
concentration range (0.001–153.3 and 176.64–351.6 μM),
a low detection limit (0.8 nM), higher sensitivity (4.98 μA
μM–1 cm–2), appreciable
selectivity, increased operational stability (2200 s), and good cycle
stability (60 cycles). The electrochemical performance of YVO4@CN indicates its practical application in real-time sample
analysis of several families of nitroimidazole drugs.
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