Purpose: Opioid analgesics are frequently dispensed in children despite its known risk in children with a compromised airway function. The objectives of the study were to assess the prevalence of opioid analgesic dispensing in children with current asthma and to identify patient and prescriber factors associated with the dispensing of opioid versus non-opioid analgesics.Methods: Children <18 years of age, having current asthma and receiving an incident analgesic prescription were identified from a large Medicaid Managed Care Plan during years 2013 through 2018. Current asthma was defined as both receiving an asthma diagnosis and filling an anti-asthmatic medication during the 12-month period prior to the analgesic medication initiation. A scoring algorithm was applied to associate analgesic prescription with procedures and diagnoses according to perceived need for analgesia and time proximity.Results: Of the 9529 children meeting the inclusion criteria, 2681 (28.1%) received an opioid prescription. Opioid analgesic dispensing was most common among children who had an outpatient surgery/procedure (29.4%), trauma (19.4%) dental procedure (18.4%), and respiratory infection (10.6%). Multivariable analysis indicated that non-Hispanic Black (AOR: 0.39[0.3-0.5]) and Hispanic (AOR: 0.51[0.4-0.6]) children were less likely to receive an opioid analgesic compared to their non-Hispanic White counterparts. Children with prior history of asthma-related emergency department visit (AOR: 1.24[1.0-1.5]) and short acting beta agonist overuse (AOR: 1.33[1.1-1.7]) were more likely to fill an opioid analgesic prescription than those without.
Conclusion:Opioid analgesics are frequently dispensed to children with asthma. A higher dispensing rate was observed among non-Hispanic White children and among those with a history of uncontrolled asthma.
2018 Medicare reimbursement amounts. Additional analysis was performed to estimate cost of unintended pregnancy when accounting for insurance status/payer (private, public, uninsured) to reflect higher unit cost paid by private insurance.
A169to married women after adjusting for age, race, AJCC stage, and ER positivity (HR 1.33, 95% CI 1.29, 1.37). ConClusions: Unmarried women are more likely to present with more advanced disease and have a higher risk of death from breast cancer. Attention should be paid to marital status in young women at the time of diagnosis. Unmarried women may benefit from additional counseling, psychosocial support, and case management to ensure their overall outcomes are optimized.
PCN200Breast CaNCer HosPital DisCHarges iN CHileaN WomeN: 10 Years aNalYsis
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