Plants have been one of the important sources of therapeutics or other human health benefits  since the beginning of human civilization throughout history. Currently, there is increasing awareness and general acceptability of the use of herbs, as a medicines, health products, pharmaceuticals, food supplements, cosmetics etc. Traditional system of medicine including Ayurveda, Unani, and Siddha etc. contributed in Health care dealing worldwide. The Unani system of medicine (USM) is an age old system of medicine which has a holistic approach to treat various kind of disease; most of the time the drugs mentioned in this system has tremendous effects in chronic disease. Asl-Us-Soos (Glycyrrhiza glabra Linn), is a widely used herb in USM. Although the review articles on this plant are already published, this review article is presented to comply all the updated information on its therapeutic potency based on phytoconstituents and pharmacological activities and the potency which is described by renowned Unani physicians and scholars. The evidence based studies provides strengthen to the concept of Unani physicians as the Unani physician used and recommended the drug since along. Moreover the evidence based studies indicate that Glycyrrhiza glabra Linn possesses antibacterial, antioxidant, antimalarial, antispasmodic, expectorant, aphrodisiac, antimycobacterial activity, antiinflammatory and anti-hyper glycemic properties. Various other effects like antiulcer, antiviral, antihepatotoxic, antifungal and herpes simplex have also been studies. These results are very encouraging and indicate that this Unani drug can be studies more extensively with a well-planned and systematic scientific preclinical and clinical approach to explore the promising outcome. Further this review gives an account of the current knowledge on the morphological characters, microscopic characters, phytochemistry, and pharmacological actions present in root of Glycyrrhiza glabra along with its actions and therapeutic potential in the perspective of USM. Keywords: Glycyrrhiza glabra, therapeutic potential, USM

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Berberis aristata DC. (Rasaut) is a frequently used herbal drug in Unani and other traditional system of medicine. It is an erect spinous and deciduous evergreen shrub belonging to the family Berberidaceae. It contains mainly berberine alkaloids which is well known for isoquinoline, that is commonly used for the treatment of gastrointestinal disorders and also used as an antibiotic agent. In Unani System of Medicine (USM) it is externally used in hot temperament inflammations, Otorrhea, pharyngitis, conjunctivitis and many of eye diseases viz Stye, Blepharitis, Epiphora, eyes itching etc. while internally used in bleeding piles, intestinal ulcers, various skin diseases alone and with other blood purifier drugs, ophthalmia, melasma, paronychia, hemorrhage, herpes, eczema, hemoptysis, splenomegaly, diarrhea, malaria, intestinal ulcers, diphtheria, dysentery, chronic leucorrhea, pruritus ani, anal fissures, menorrhagia and jaundice. Different type of active phytoconstituents have also been evaluated from Rasaut which includes alkaloids, glycosides, flavonoids, phenolic compounds, tannins, saponins, steroids, E-caffeic acid, chlorogenic acid, carbohydrate, volatile oils, fixed oils and fats. The present work is based on search available about review and analysis of related articles published in various reputed journals using the phrases “Rasaut or Berberis aristata”, “Rasaut and Unani Medicine” “Rasaut research paper”, and “Rasaut used in traditional medicine” in electronic searches of the Google Scholar advanced search, PubMed, Scopus, ResearchGate, Web of Science and AYUSH Research Portal etc.In this review, it is tried to compiled all the available information till date from both Unani and other published scientific papers and textbooks regarding the therapeutic properties, pharmacological activities and traditional values of Berberis aristata, which will be fruitful for researchers to design further in vitro and in vivo scientific studies to explore the more medicinal values along with biomolecules of Berberis aristata DC.